CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031203
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Polypyrimidine tract-binding protein 2 
Protein Synonyms/Alias
 cDNA FLJ55936, highly similar to Polypyrimidine tract-binding protein 2 
Gene Name
 PTBP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
267TLRIDFSKLVNLNVKubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MWSNLTFSFF GLRTKAKKYV TVNNRGSDEL LSGSVLSSPN SNMSSMVVTA NGNDSKKFKG 60
EDKMDGAPSR VLHIRKLPGE VTETEVIALG LPFGKVTNIL MLKGKNQAFL ELATEEAAIT 120
MVNYYSAVTP HLRNQPIYIQ YSNHKELKTD NTLNQRAQAV LQAVTAVQTA NTPLSGTTVS 180
ESAVTPAQSP VLRIIIDNMY YPVTLDVLHQ IFSKFGAVLK IITFTKNNQF QALLQYGDPV 240
NAQQAKLALD GQNIYNACCT LRIDFSKLVN LNVKYNNDKS RDYTRPDLPS GDGQPALDPA 300
IAAAFAKETS LLGLPVAAVP GALSPLAIPN AAAAAAAAAA GRVGMPGVSA GGNTVLLVSN 360
LNEEMVTPQS LFTLFGVYGD VQRVKILYNK KDSALIQMAD GNQSQLAMNH LNGQKMYGKI 420
IRVTLSKHQT VQLPREGLDD QGLTKDFGNS PLHRFKKPGS KNFQNIFPPS ATLHLSNIPP 480
SVAEEDLRTL FANTGGTVKA FKFFQRDHKM ALLQMATVEE AIQALIDLHN YNLGENHHLR 540
VSFSKSTI 548 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:InterPro. 
Interpro
 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS