CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041859
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear receptor subfamily 2 group C member 2 
Protein Synonyms/Alias
 Nuclear receptor subfamily 2, group C, member 2, isoform CRA_a 
Gene Name
 Nr2c2 
Gene Synonyms/Alias
 mCG_127892 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
264TPTFVADKDGARQTGacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 629 AA 
Protein Sequence
MATNMEGLVQ HRVGTQQVAE VPRTQTSWPE SPGMTSPSPR IQIISTDSAV ASPQRIQIVT 60
DQQTGQKIQI VTAVDASGSS KQQFILTSPD GAGTGKVILA SPETSSAKQL IFTTSDNLVP 120
GRIQIVTDSA SVERLLGKAD VQRPQVVEYC VVCGDKASGR HYGAVSCEGC KGFFKRSVRK 180
NLTYSCRSSQ DCIINKHHRN RCQFCRLKKC LEMGMKMESV QSERKPFDVQ REKPSNCAAS 240
TEKIYIRKDL RSPLIATPTF VADKDGARQT GLLDPGMLVN IQQPLIREDG TVLLAADSKA 300
ETSQGALGTL ANVVTSLANL SESLNNGDAS EMQPEDQSAS EITRAFDTLA KALNTTDSAS 360
PPSLADGIDA SGGGSIHVIS RDQSTPIIEV EGPLLSDTHV TFKLTMPSPM PEYLNVHYIC 420
ESASRLLFLS MHWARSIPAF QALGQDCNTS LVRACWNELF TLGLAQCAQV MSLSTILAAI 480
VNHLQNSIQE DKLSGDRIKQ VMEHIWKLQE FCNSMAKLDI DGYEYAYLKA IVLFSPDHPG 540
LTGTSQIEKF QEKAQMELQD YVQKTYSEDT YRLARILVRL PALRLMSSNI TEELFFTGLI 600
GNVSIDSIIP YILKMETAEY NGQITGASL 629 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0051321; P:meiotic cell cycle; IMP:MGI.
 GO:0007283; P:spermatogenesis; IMP:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR000536; Nucl_hrmn_rcpt_lig-bd_core.
 IPR001723; Str_hrmn_rcpt.
 IPR001628; Znf_hrmn_rcpt.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00104; Hormone_recep
 PF00105; zf-C4 
SMART
 SM00430; HOLI
 SM00399; ZnF_C4 
PROSITE
 PS00031; NUCLEAR_REC_DBD_1
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR00398; STRDHORMONER.
 PR00047; STROIDFINGER.