CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026469
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 
Protein Synonyms/Alias
 Electron transferring flavoprotein dehydrogenase; Electron-transferring-flavoprotein dehydrogenase 
Gene Name
 Etfdh 
Gene Synonyms/Alias
 ETFDH; rCG_62537 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
95QLAAEQEKDIRVCLVacetylation[1]
124CLDPAAFKELFPDWKacetylation[1]
131KELFPDWKEKGAPLNacetylation[1]
152RFAILTEKHRIPVPIacetylation[1]
222TNDVGIQKDGAPKTTacetylation[1]
283ELWVIDEKKWKPGRVacetylation[1]
356RPTLEGGKRIAYGARacetylation[1]
415LAAEAIFKQLTSENLacetylation[1]
445LKQSWVWKELHAVRNacetylation[1]
486GMEPWTLKHKGSDSEacetylation[1]
496GSDSEQLKPAKDCTPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 616 AA 
Protein Sequence
MLVRLTKLSC PAYQWFHALK IKKCLPLCAP RCSSTSAVPQ ITTHYTIHPR EKDKRWEGVN 60
MERFAEEADV VIVGAGPAGL SAAIRLKQLA AEQEKDIRVC LVEKAAQIGA HTLSGACLDP 120
AAFKELFPDW KEKGAPLNTP VTEDRFAILT EKHRIPVPIL PGLPMNNHGN YIVRLGHLVS 180
WMGEQAEALG VEVYPGYAAA EVLYHEDGSV KGIATNDVGI QKDGAPKTTF ERGLELHAKV 240
TIFAEGCHGH LAKQLYKKFD LRASCDAQTY GIGLKELWVI DEKKWKPGRV DHTVGWPLDR 300
HTYGGSFLYH LNEGEPLVAV GFVVGLDYQN PYLSPFREFQ RWKHHPSIRP TLEGGKRIAY 360
GARALNEGGL QSIPKLTFPG GLLIGCSPGF MNVPKIKGTH TAMKSGSLAA EAIFKQLTSE 420
NLQSKTAGLH VTEYEDNLKQ SWVWKELHAV RNIRPSCHGI LGVYGGMIYT GIFYWILRGM 480
EPWTLKHKGS DSEQLKPAKD CTPIEYPKPD GQISFDLLSS VALSGTNHEH DQPAHLTLKD 540
DSIPVNRNLS IYDGPEQRFC PAGVYEFVPL EQGDGFRLQI NAQNCVHCKT CDIKDPSQNI 600
NWVVPEGGGG PAYNGM 616 
Gene Ontology
 GO:0031305; C:integral to mitochondrial inner membrane; IEA:Compara.
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:Compara.
 GO:0009055; F:electron carrier activity; IEA:Compara.
 GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IEA:Compara.
 GO:0048039; F:ubiquinone binding; IEA:Compara.
 GO:0022900; P:electron transport chain; IEA:Compara.
 GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IEA:Compara.
 GO:0006979; P:response to oxidative stress; IEA:Compara. 
Interpro
 IPR017896; 4Fe4S_Fe-S-bd.
 IPR007859; ETFD_OxRdtase.
 IPR000103; Pyridine_nuc-diS_OxRdtase_2. 
Pfam
 PF05187; ETF_QO 
SMART
  
PROSITE
 PS51379; 4FE4S_FER_2 
PRINTS
 PR00469; PNDRDTASEII.