CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043575
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Maltase-glucoamylase, intestinal 
Protein Synonyms/Alias
  
Gene Name
 MGA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
19KLQEKSWKSSCNEGEubiquitination[1]
150LPSTSNSKMASSSGTubiquitination[1]
200KVGALQQKIPGVSTPubiquitination[1]
563EPQSFASKTGSETKIubiquitination[2]
1052KAPPIPLKLKPDYWSubiquitination[3]
1054PPIPLKLKPDYWSDKacetylation[2]
1054PPIPLKLKPDYWSDKubiquitination[2]
1061KPDYWSDKLQKEAEAubiquitination[4]
1108LHSSKVSKSLILTRAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1174 AA 
Protein Sequence
XLTCDLEDDS DKLQEKSWKS SCNEGESSST SYMHQRSPGG PTKLIEIISD CNWEEDRNKI 60
LSILSQHINS NMPQSLKVNG KSYPQAKLLL GQMGALHPAN RLAAYITGRL RPSVLDLSTL 120
STVISKVASN AKVAASRKPR TLLPSTSNSK MASSSGTATN RPGKNLKAFV PAKRPIAARP 180
SPGGVFTQFV MSKVGALQQK IPGVSTPQTL AGTQKFSIRP SPVMVVTPVV SSEPVQVCSP 240
VTAAVTTTTP QVFLENTTAV TPMTAISDVE TKETTYSSGA TTTGVVEVSE TNTSTSVTST 300
QSTATVNLTK TTGITTPVAS VAFPKSLVAS PSTITLPVAS TASTSLVVVT AAASSSMVTT 360
PTSSLGSVPI ILSGINGSPP VSQRPENAAQ IPVATPQVSP NTVKRAGPRL LLIPVQQGSP 420
TLRPVSNTQL QGHRMVLQPV RSPSGMNLFR HPNGQIVQLL PLHQLRGSNT QPNLQPVMFR 480
NPGSVMGIRL PAPSKPSETP PSSTSSSAFS VMNPVIQAVG SSSAVNVITQ APSLLSSGAS 540
FVSQAGTLTL RISPPEPQSF ASKTGSETKI TYSSGGQPVG TASLIPLQSG SFALLQLPGQ 600
KPVPSSILQH VASLQMKRES QNPDQKDETN SIKREQETKK VLQSEGEAVD PEANVIKQNS 660
GAATSEETLN DSLEDRGDHL DEECLPEEGC ATVKPSEHSC ITGSHTDQDY KDVNEEYGAR 720
NRKSSKEKVA VLEVRTISEK ASNKTVQNLS KVQHQKLGDV KVEQQKGFDN PEENSSEFPV 780
TFKEESKFEL SGSKVMEQQS NLQPEAKEKE CGDSLEKDRE RWRKHLKGPL TRKCVGASQE 840
CKKEADEQLI KETKTCQENS DVFQQEQGIS DLLGKSGITE DARVLKTECD SWSRISNPSA 900
FSIVPRRAAK SSRGNGHFQG HLLLPGEQIQ PKQEKKGGRS SADFTVLDLE EDDEDDNEKT 960
DDSIDEIVDV VSDYQSEEVD DVEKNNCVEY IEDDEEHVDI ETVEELSEEI NVAHLKTTAA 1020
HTQSFKQPSC THISADEKAA ERSRKAPPIP LKLKPDYWSD KLQKEAEAFA YYRRTHTANE 1080
RRRRGEMRDL FEKLKITLGL LHSSKVSKSL ILTRAFSEIQ GLTDQADKLI GQKNLLTRKR 1140
NILIRKVSSL SGKTEEVVLK KLEYIYAKQQ ALEA 1174 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 
Interpro
 IPR011598; bHLH_dom.
 IPR001699; TF_T-box. 
Pfam
 PF00010; HLH 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS