| Tag | Content |
|---|
| CPLM ID | CPLM-023518 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Replication factor C subunit 2 |
Protein Synonyms/Alias | Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40 |
Gene Name | Rfc2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 171 | LACNASDKIIEPIQS | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity). |
Sequence Annotation | NP_BIND 71 78 ATP (Potential).
MOD_RES 158 158 N6-acetyllysine (By similarity).
MOD_RES 299 299 N6-acetyllysine (By similarity). |
Keyword | Acetylation; ATP-binding; Complete proteome; DNA replication; Nucleotide-binding; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 349 AA |
Protein Sequence | MEVQESGCDP SESGAQEPSP VPSKTAGHYE LPWVEKYRPL KLNEIVGNED TVSRLEVFAR 60
EGNVPNIIIA GPPGTGKTTS ILCLARALLG PALKDAVLEL NASNDRGIDV VRNKIKMFAQ 120
QKVTLPKGRH KIIILDEADS MTDGAQQALR RTMEIYSKTT RFALACNASD KIIEPIQSRC 180
AVLRYTKLTD AQVLTRLMNV IEKEKVPYTD DGLEAIIFTA QGDMRQALNN LQSTFSGFGY 240
INSENVFKVC DEPHPLLVKE MIQHCVDANI DEAYKILAHL WHLGYSPEDV IGNIFRVCKT 300
FPMAEYLKLE FIKEIGYTHM KVAEGVNSLL QMAGLLARLC QKTMAPVAS 349 |
Gene Ontology | GO:0005663; C:DNA replication factor C complex; IEA:Compara. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003677; F:DNA binding; IEA:InterPro. GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. GO:0006260; P:DNA replication; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |