UniProt Accession

 D6RAB1_HUMAN; D6RAB1 

Genbank Protein ID

 AC092539; AC097067; AC118062; AC123576 

Genbank Nucleotide ID

  

Protein Name

 Lymphoid enhancer-binding factor 1 

Protein Synonyms/Alias

  

Gene Name

 LEF1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
18	SQEPYHDKAREHPDD	acetylation	[1]
18	SQEPYHDKAREHPDD	ubiquitination	[2]
27	REHPDDGKHPDGGLY	acetylation	[1]
27	REHPDDGKHPDGGLY	ubiquitination	[1, 2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 173 AA 

Protein Sequence

Gene Ontology

 GO:0016055; P:Wnt receptor signaling pathway; IEA:InterPro. 

Interpro

 IPR013558; CTNNB1-bd_N.
 IPR024940; TCF/LEF. 

Pfam

 PF08347; CTNNB1_binding 

SMART

  

PROSITE

  

PRINTS