CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002167
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arginine permease 
Protein Synonyms/Alias
  
Gene Name
 CAN1 
Gene Synonyms/Alias
 YEL063C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
5***MTNSKEDADIEEubiquitination[1]
42RRGSIPLKDEKSKELubiquitination[1]
47PLKDEKSKELYPLRSubiquitination[1]
85EVQNAEVKRELKQRHubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 High-affinity permease for arginine. 
Sequence Annotation
 REGION 1 92 Hydrophilic.
 REGION 549 590 Hydrophilic.  
Keyword
 Amino-acid transport; Cell membrane; Complete proteome; Endosome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 590 AA 
Protein Sequence
MTNSKEDADI EEKHMYNEPV TTLFHDVEAS QTHHRRGSIP LKDEKSKELY PLRSFPTRVN 60
GEDTFSMEDG IGDEDEGEVQ NAEVKRELKQ RHIGMIALGG TIGTGLFIGL STPLTNAGPV 120
GALISYLFMG SLAYSVTQSL GEMATFIPVT SSFTVFSQRF LSPAFGAANG YMYWFSWAIT 180
FALELSVVGQ VIQFWTYKVP LAAWISIFWV IITIMNLFPV KYYGEFEFWV ASIKVLAIIG 240
FLIYCFCMVC GAGVTGPVGF RYWRNPGAWG PGIISKDKNE GRFLGWVSSL INAAFTFQGT 300
ELVGITAGEA ANPRKSVPRA IKKVVFRILT FYIGSLLFIG LLVPYNDPKL TQSTSYVSTS 360
PFIIAIENSG TKVLPHIFNA VILTTIISAA NSNIYVGSRI LFGLSKNKLA PKFLSRTTKG 420
GVPYIAVFVT AAFGALAYME TSTGGDKVFE WLLNITGVAG FFAWLFISIS HIRFMQALKY 480
RGISRDELPF KAKLMPGLAY YAATFMTIII IIQGFTAFAP KFNGVSFAAA YISIFLFLAV 540
WILFQCIFRC RFIWKIGDVD IDSDRRDIEA IVWEDHEPKT FWDKFWNVVA 590 
Gene Ontology
 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0045121; C:membrane raft; IDA:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0015181; F:arginine transmembrane transporter activity; IMP:SGD. 
Interpro
 IPR004841; AA-permease_dom.
 IPR002293; AA/rel_permease1.
 IPR004762; Amino_acid_permease_fungi.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
 PF00324; AA_permease 
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS