CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031250
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Absent in melanoma 1 protein 
Protein Synonyms/Alias
 Absent in melanoma 1, isoform CRA_a; cDNA FLJ61405, highly similar to Absent in melanoma 1 protein 
Gene Name
 AIM1 
Gene Synonyms/Alias
 hCG_33516 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
151SEKNFGSKGSSIDVLubiquitination[1, 2]
165LGIVANLKETGYGVKubiquitination[1]
215DWGGKNCKISSVQPIubiquitination[1]
335REDFKGKKIELNAETubiquitination[1]
430NGNLEDLKLLRIQVMubiquitination[1]
528IILNTVSKEKFTQVWubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 542 AA 
Protein Sequence
MQKPKTVAWE NLGPEMSALG TAFSREGGRK VEFPTDPKVV VYEKPFFEGK CVELETGMCS 60
FVMEGGETEE ATGDDHLPFT SVGSMKVLRG IWVAYEKPGF TGHQYLLEEG EYRDWKAWGG 120
YNGELQSLRP ILGDFSNAHM IMYSEKNFGS KGSSIDVLGI VANLKETGYG VKTQSINVLS 180
GVWVAYENPD FTGEQYILDK GFYTSFEDWG GKNCKISSVQ PICLDSFTGP RRRNQIHLFS 240
EPQFQGHSQS FEETTSQIDD SFSTKSCRVS GGSWVVYDGE NFTGNQYVLE EGHYPCLSAM 300
GCPPGATFKS LRFIDVEFSE PTIILFERED FKGKKIELNA ETVNLRSLGF NTQIRSVQVI 360
GGIWVTYEYG SYRGRQFLLS PAEVPNWYEF SGCRQIGSLR PFVQKRIYFR LRNKATGLFM 420
STNGNLEDLK LLRIQVMEDV GADDQIWIYQ EGCIKCRIAE DCCLTIVGSL VTSGSKLGLA 480
LDQNADSQFW SLKSDGRIYS KLKPNLVLDI KGGTQYDQNH IILNTVSKEK FTQVWEAMVL 540
YT 542 
Gene Ontology
  
Interpro
 IPR001064; Beta/gamma_crystallin.
 IPR011024; G_crystallin-rel.
 IPR000772; Ricin_B_lectin. 
Pfam
 PF00030; Crystall
 PF00652; Ricin_B_lectin 
SMART
 SM00458; RICIN
 SM00247; XTALbg 
PROSITE
 PS50915; CRYSTALLIN_BETA_GAMMA
 PS50231; RICIN_B_LECTIN 
PRINTS
 PR01367; BGCRYSTALLIN.