UniProt Accession

 HSC20_MOUSE; Q8K3A0; Q3V294 

Genbank Protein ID

 AK131961; BC027641 

Genbank Nucleotide ID

 BAE20904.1; AAH27641.1 

Protein Name

 Iron-sulfur cluster co-chaperone protein HscB, mitochondrial 

Protein Synonyms/Alias

 Hsc20 

Gene Name

 Hscb 

Gene Synonyms/Alias

 Hsc20 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
209	FEQGDFEKAKELLTK	acetylation	[1]

Reference

 [1] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379] 

Functional Description

 Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria (By similarity). 

Sequence Annotation

 DOMAIN 71 143 J.
 METAL 40 40 Divalent metal cation (By similarity).
 METAL 43 43 Divalent metal cation (By similarity).
 METAL 57 57 Divalent metal cation (By similarity).
 METAL 60 60 Divalent metal cation (By similarity).  

Keyword

 Chaperone; Complete proteome; Cytoplasm; Metal-binding; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 234 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0016226; P:iron-sulfur cluster assembly; IEA:Compara.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0051259; P:protein oligomerization; IEA:InterPro. 

Interpro

 IPR001623; DnaJ_domain.
 IPR004640; HscB.
 IPR009073; HscB_oligo_C. 

Pfam

 PF00226; DnaJ
 PF07743; HSCB_C 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2 

PRINTS