UniProt Accession

 PEX14_MOUSE; Q9R0A0 

Genbank Protein ID

 AF097512; BC028952 

Genbank Nucleotide ID

 AAF04616.1; AAH28952.1 

Protein Name

 Peroxisomal membrane protein PEX14 

Protein Synonyms/Alias

 PTS1 receptor-docking protein; Peroxin-14; Peroxisomal membrane anchor protein PEX14 

Gene Name

 Pex14 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
195	AHELATAKATTSTNW	ubiquitination	[1]
220	KSEINSLKGLLLNRR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17 (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 34 34 N6-acetyllysine (By similarity).
 MOD_RES 280 280 Phosphoserine.
 MOD_RES 334 334 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Membrane; Peroxisome; Phosphoprotein; Protein transport; Reference proteome; Translocation; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:Compara.
 GO:0005778; C:peroxisomal membrane; IDA:MGI.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0003714; F:transcription corepressor activity; IEA:InterPro.
 GO:0034453; P:microtubule anchoring; IEA:Compara.
 GO:0032091; P:negative regulation of protein binding; IEA:Compara.
 GO:1901094; P:negative regulation of protein homotetramerization; IEA:Compara.
 GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0036250; P:peroxisome transport along microtubule; IEA:Compara.
 GO:0051260; P:protein homooligomerization; IEA:Compara.
 GO:0044721; P:protein import into peroxisome matrix, substrate release; IEA:Compara.
 GO:0016561; P:protein import into peroxisome matrix, translocation; IEA:Compara. 

Interpro

 IPR025655; PEX14.
 IPR006785; Pex14_N. 

Pfam

 PF04695; Pex14_N 

SMART

  

PROSITE

  

PRINTS