CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024744
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Chchd6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
197EKNAELYKLSSQQFHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Required for maintaining mitochondrial crista morphology, ATP production and oxygen consumption (By similarity). 
Sequence Annotation
 DOMAIN 216 257 CHCH.
 LIPID 2 2 N-myristoyl glycine (Potential).
 DISULFID 223 254 By similarity.
 DISULFID 233 244 By similarity.  
Keyword
 Coiled coil; Complete proteome; Disulfide bond; Lipoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Myristate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MGSSESAEAR RVSFEMDEEE RVRVLQGIRL SESVVNRMKD CSQPSAGEQL APGPGPECSV 60
PVPTVPQPTI PVLTVPSPSV CGPAEGTYKA PQGDFKVSRA ENSDGQQSSA VKEDLKKFQQ 120
EQLAVQDELV KVARKEKEAT EKHLKASLPK KKATHEQQQS DRLTRELKNR EAELSRRDTF 180
YKEQQERIQE KNAELYKLSS QQFHEAASKA ESTIKPRRVE PVCSGLQAQI LRCYRDHLHE 240
VLLCSDLAKA YQHCVSTARK G 261 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
 GO:0042407; P:cristae formation; ISS:UniProtKB.
 GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB. 
Interpro
 IPR007964; DUF737. 
Pfam
 PF05300; DUF737 
SMART
  
PROSITE
  
PRINTS