| Tag | Content |
|---|
| CPLM ID | CPLM-004135 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Myosin heavy chain, skeletal muscle, adult |
Protein Synonyms/Alias | |
Gene Name | |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Gallus gallus (Chicken) |
NCBI Taxa ID | 9031 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 36 | QNKPFDAKSSVFVVH | methylation | [1] | | 131 | CVTVNPYKWLPVYNP | methylation | [1] | | 552 | KATDTSFKNKLYDQH | methylation | [1] |
|
Reference | [1] Update on activities at the Universal Protein Resource (UniProt) in 2013. e="String">UniProt Consortium. Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [ PMID: 23161681] |
Functional Description | Muscle contraction. Myosin is a protein that binds to F- actin and has ATPase activity that is activated by F-actin. |
Sequence Annotation | DOMAIN 2 783 Myosin head-like.
DOMAIN 784 813 IQ.
NP_BIND 180 187 ATP (Potential).
REGION 658 680 Actin-binding.
REGION 760 774 Actin-binding.
REGION 839 841 Hinge.
MOD_RES 2 2 N-acetylalanine.
MOD_RES 36 36 N6-methyllysine.
MOD_RES 131 131 N6,N6,N6-trimethyllysine.
MOD_RES 552 552 N6,N6,N6-trimethyllysine.
MOD_RES 756 756 Pros-methylhistidine. |
Keyword | 3D-structure; Acetylation; Actin-binding; ATP-binding; Calmodulin-binding; Coiled coil; Complete proteome; Cytoplasm; Direct protein sequencing; Methylation; Motor protein; Muscle protein; Myosin; Nucleotide-binding; Phosphoprotein; Reference proteome; Thick filament. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1939 AA |
Protein Sequence | MASPDAEMAA FGEAAPYLRK SEKERIEAQN KPFDAKSSVF VVHPKESFVK GTIQSKEGGK 60
VTVKTEGGET LTVKEDQVFS MNPPKYDKIE DMAMMTHLHE PAVLYNLKER YAAWMIYTYS 120
GLFCVTVNPY KWLPVYNPEV VLAYRGKKRQ EAPPHIFSIS DNAYQFMLTD RENQSILITG 180
ESGAGKTVNT KRVIQYFATI AASGEKKKEE QSGKMQGTLE DQIISANPLL EAFGNAKTVR 240
NDNSSRFGKF IRIHFGATGK LASADIETYL LEKSRVTFQL PAERSYHIFY QIMSNKKPEL 300
IDMLLITTNP YDYHYVSQGE ITVPSIDDQE ELMATDSAID ILGFSADEKT AIYKLTGAVM 360
HYGNLKFKQK QREEQAEPDG TEVADKAAYL MGLNSAELLK ALCYPRVKVG NEFVTKGQTV 420
SQVHNSVGAL AKAVYEKMFL WMVIRINQQL DTKQPRQYFI GVLDIAGFEI FDFNSFEQLC 480
INFTNEKLQQ FFNHHMFVLE QEEYKKEGIE WEFIDFGMDL AACIELIEKP MGIFSILEEE 540
CMFPKATDTS FKNKLYDQHL GKSNNFQKPK PAKGKAEAHF SLVHYAGTVD YNISGWLEKN 600
KDPLNETVIG LYQKSSVKTL ALLFATYGGE AEGGGGKKGG KKKGSSFQTV SALFRENLNK 660
LMANLRSTHP HFVRCIIPNE TKTPGAMEHE LVLHQLRCNG VLEGIRICRK GFPSRVLYAD 720
FKQRYRVLNA SAIPEGQFMD SKKASEKLLG SIDVDHTQYR FGHTKVFFKA GLLGLLEEMR 780
DDKLAEIITR TQARCRGFLM RVEYRRMVER RESIFCIQYN VRSFMNVKHW PWMKLFFKIK 840
PLLKSAESEK EMANMKEEFE KTKEELAKSE AKRKELEEKM VVLLQEKNDL QLQVQAEADS 900
LADAEERCDQ LIKTKIQLEA KIKEVTERAE DEEEINAELT AKKRKLEDEC SELKKDIDDL 960
ELTLAKVEKE KHATENKVKN LTEEMAVLDE TIAKLTKEKK ALQEAHQQTL DDLQVEEDKV 1020
NTLTKAKTKL EQQVDDLEGS LEQEKKLRMD LERAKRKLEG DLKLAHDSIM DLENDKQQLD 1080
EKLKKKDFEI SQIQSKIEDE QALGMQLQKK IKELQARIEE LEEEIEAERT SRAKAEKHRA 1140
DLSRELEEIS ERLEEAGGAT AAQIEMNKKR EAEFQKMRRD LEEATLQHEA TAAALRKKHA 1200
DSTAELGEQI DNLQRVKQKL EKEKSELKME IDDLASNMES VSKAKANLEK MCRTLEDQLS 1260
EIKTKEEQNQ RMINDLNTQR ARLQTETGEY SRQAEEKDAL ISQLSRGKQG FTQQIEELKR 1320
HLEEEIKAKN ALAHALQSAR HDCELLREQY EEEQEAKGEL QRALSKANSE VAQWRTKYET 1380
DAIQRTEELE EAKKKLAQRL QDAEEHVEAV NAKCASLEKT KQRLQNEVED LMVDVERSNA 1440
ACAALDKKQK NFDKILAEWK QKYEETQTEL EASQKESRSL STELFKMKNA YEESLDHLET 1500
LKRENKNLQQ EIADLTEQIA EGGKAVHELE KVKKHVEQEK SELQASLEEA EASLEHEEGK 1560
ILRLQLELNQ IKSEIDRKIA EKDEEIDQLK RNHLRIVESM QSTLDAEIRS RNEALRLKKK 1620
MEGDLNEMEI QLSHANRMAA EAQKNLRNTQ GTLKDTQIHL DDALRTQEDL KEQVAMVERR 1680
ANLLQAEVEE LRGALEQTER SRKVAEQELL DATERVQLLH TQNTSLINTK KKLETDIVQI 1740
QSEMEDTIQE ARNAEEKAKK AITDAAMMAE ELKKEQDTSA HLERMKKNMD QTVKDLHVRL 1800
DEAEQLALKG GKKQLQKLEA RVRELEGEVD SEQKRSAEAV KGVRKYERRV KELTYQCEED 1860
RKNILRLQDL VDKLQMKVKS YKRQAEEAEE LSNVNLSKFR KIQHELEEAE ERADIAESQV 1920
NKLRVKSREI HGKKIEEEE 1939 |
Gene Ontology | |
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Pfam | |
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