CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kelch-like protein 2 
Protein Synonyms/Alias
 cDNA FLJ60241, highly similar to Kelch-like protein 2 
Gene Name
 KLHL2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
163SVECYDFKEERWHQVubiquitination[1]
345HDGPLVRKSVEVYDPubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kelch repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 427 AA 
Protein Sequence
MHACTDLLNK ANTYAEQHFA DVVLSEEFLN LGIEQVCSLI SSDKLTISSE EKVFEAVIAW 60
VNHDKDVRQE FMARLMEHVR LPLLPREYLV QRVEEEALVK NSSACKDYLI EAMKYHLLPT 120
EQRILMKSVR TRLRTPMNLP KLMVVVGGQA PKAIRSVECY DFKEERWHQV AELPSRRCRA 180
GMVYMAGLVF AVGGFNGSLR VRTVDSYDPV KDQWTSVANM RDRRSTLGAA VLNGLLYAVG 240
GFDGSTGLSS VEAYNIKSNE WFHVAPMNTR RSSVGVGVVG GLLYAVGGYD GASRQCLSTV 300
ECYNATTNEW TYIAEMSTRR SGAGVGVLNN LLYAVGGHDG PLVRKSVEVY DPTTNAWRQV 360
ADMNMCRRNA GVCAVNGLLY VVGGDDGSCN LASVEYYNPT TDKWTVVSSC MSTGRSYAGV 420
TVIDKPL 427 
Gene Ontology
  
Interpro
 IPR011705; BACK.
 IPR015916; Gal_Oxidase_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF07707; BACK
 PF01344; Kelch_1 
SMART
 SM00875; BACK
 SM00612; Kelch 
PROSITE
  
PRINTS