CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007676
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Syndecan-2 
Protein Synonyms/Alias
 SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD362 
Gene Name
 Sdc2 
Gene Synonyms/Alias
 Hspg1; Synd2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
175LVYRMRKKDEGSYDLubiquitination[1]
194PSSAAYQKAPTKEFYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis. 
Sequence Annotation
 MOD_RES 188 188 Phosphoserine (By similarity).
 CARBOHYD 41 41 O-linked (Xyl...) (heparan sulfate)
 CARBOHYD 55 55 O-linked (Xyl...) (heparan sulfate)
 CARBOHYD 57 57 O-linked (Xyl...) (heparan sulfate)  
Keyword
 Complete proteome; Differentiation; Glycoprotein; Heparan sulfate; Membrane; Neurogenesis; Phosphoprotein; Proteoglycan; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MQRAWILLTL GLMACVSAET RTELTSDKDM YLDNSSIEEA SGVYPIDDDD YSSASGSGAD 60
EDIESPVLTT SQLIPRIPLT SAASPKVETM TLKTQSITPA QTESPEETDK EEVDISEAEE 120
KLGPAIKSTD VYTEKHSDNL FKRTEVLAAV IAGGVIGFLF AIFLILLLVY RMRKKDEGSY 180
DLGERKPSSA AYQKAPTKEF YA 202 
Gene Ontology
 GO:0005796; C:Golgi lumen; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0048813; P:dendrite morphogenesis; IEA:Compara.
 GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
 GO:0031000; P:response to caffeine; IEA:Compara.
 GO:0001666; P:response to hypoxia; IEA:Compara.
 GO:0042060; P:wound healing; IEA:Compara. 
Interpro
 IPR003585; Neurexin-like.
 IPR001050; Syndecan. 
Pfam
 PF01034; Syndecan 
SMART
 SM00294; 4.1m 
PROSITE
 PS00964; SYNDECAN 
PRINTS