CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037717
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transcription factor BTF3 homolog 4 
Protein Synonyms/Alias
  
Gene Name
 BTF3L4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18AQVRIGGKGTARRKKacetylation[1]
18AQVRIGGKGTARRKKubiquitination[2]
115DSLTSLRKLAEQFPRubiquitination[3, 4, 5, 6]
Reference
 [1] Identification of lysine acetyltransferase p300 substrates using 4-pentynoyl-coenzyme A and bioorthogonal proteomics.
 Yang YY, Grammel M, Hang HC.
 Bioorg Med Chem Lett. 2011 Sep 1;21(17):4976-9. [PMID: 21669532]
 [2] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [3] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048]
 [4] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [5] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [6] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 145 AA 
Protein Sequence
MNQEKLAKLQ AQVRIGGKGT ARRKKKVVHR TATADDKKLQ SSLKKLAVNN IAGIEEVNMI 60
KDDGTVIHFN NPKVQASLSA NTFAITGHAE AKPITEMLPG ILSQLGADSL TSLRKLAEQF 120
PRQVLDSKAP KPEDIDEEDD DVPGK 145 
Gene Ontology
  
Interpro
 IPR002715; Nas_poly-pep-assoc_cplx_dom. 
Pfam
 PF01849; NAC 
SMART
  
PROSITE
 PS51151; NAC_AB 
PRINTS