CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017104
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Copine-9 
Protein Synonyms/Alias
 Copine IX 
Gene Name
 CPNE9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
132LTGVPGKKCGTILLTacetylation[1]
158TMQLCANKLDKKDFFacetylation[1]
161LCANKLDKKDFFGKSacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity). 
Sequence Annotation
 DOMAIN 1 107 C2 1.
 DOMAIN 134 239 C2 2.
 DOMAIN 299 500 VWFA.
 CARBOHYD 95 95 N-linked (GlcNAc...).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 553 AA 
Protein Sequence
MSLGGASERS VPATKIEITV SCRNLLDLDT FSKSDPMVVL YTQSRASQEW REFGRTEVID 60
NTLNPDFVRK FVLDYFFEEK QNLRFDVYNV DSKTNISKPK DFLGQAFLAL GEVIGGQGSR 120
VERTLTGVPG KKCGTILLTA EELSNCRDIA TMQLCANKLD KKDFFGKSDP FLVFYRSNED 180
GTFTICHKTE VVKNTLNPVW QPFSIPVRAL CNGDYDRTVK IDVYDWDRDG SHDFIGEFTT 240
SYRELSKAQN QFTVYEVLNP RKKCKKKKYV NSGTVTLLSF SVDSEFTFVD YIKGGTQLNF 300
TVAIDFTASN GNPLQPTSLH YMSPYQLSAY AMALKAVGEI IQDYDSDKLF PAYGFGAKLP 360
PEGRISHQFP LNNNDEDPNC AGIEGVLESY FQSLRTVQLY GPTYFAPVIN QVARAAAKIS 420
DGSQYYVLLI ITDGVISDMT QTKEAIVSAS SLPMSIIIVG VGPAMFEAME ELDGDDVRVS 480
SRGRYAERDI VQFVPFRDYV DRSGNQVLSM ARLAKDVLAE IPEQLLSYMR TRDIQPRPPP 540
PANPSPIPAP EQP 553 
Gene Ontology
  
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR010734; Copine.
 IPR002035; VWF_A. 
Pfam
 PF00168; C2
 PF07002; Copine 
SMART
 SM00239; C2
 SM00327; VWA 
PROSITE
 PS50004; C2
 PS50234; VWFA 
PRINTS