| Tag | Content |
|---|
| CPLM ID | CPLM-004800 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanylate cyclase soluble subunit alpha-3 |
Protein Synonyms/Alias | GCS-alpha-3; GCS-alpha-1; Soluble guanylate cyclase large subunit |
Gene Name | Gucy1a3 |
Gene Synonyms/Alias | Guc1a1; Gucy1a1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 110 | ENRNSSEKEDLERII | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | |
Sequence Annotation | DOMAIN 480 607 Guanylate cyclase. |
Keyword | cGMP biosynthesis; Complete proteome; Cytoplasm; Direct protein sequencing; GTP-binding; Lyase; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 690 AA |
Protein Sequence | MFCRKFKDLK ITGECPFSLL APGQVPTEPI EEVAGVSESC QATLPTCQEF AENAEGSHPQ 60
RKTSRNRVYL HTLAESIGKL IFPEFERLNL ALQRTLAKHK IKENRNSSEK EDLERIIAEE 120
AIAAGVPVEV LKDSLGEELF KICYEEDEHI LGVVGGTLKD FLNSFSTLLK QSSHCQEAER 180
RGRLEDASIL CLDKDQDFLN VYYFFPKRTT ALLLPGIIKA AARILYESHV EVSLMPPCFR 240
SECTEFVNQP YLLYSVHVKS TKPSLSPGKP QSSLVIPTSL FCKTFPFHFM LDRDLAILQL 300
GNGIRRLVNK RDFQGKPNFE EFFEILTPKI NQTFSGIMTM LNMQFVIRVR RWDNLVKKSS 360
RVMDLKGQMI YIVESSAILF LGSPCVDRLE DFTGRGLYLS DIPIHNALRD VVLIGEQARA 420
QDGLKKRLGK LKATLEHAHQ ALEEEKKKTV DLLCSIFPSE VAQQLWQGQI VQAKKFNEVT 480
MLFSDIVGFT AICSQCSPLQ VITMLNALYT RFDQQCGELD VYKVETIGDA YCVAGGLHRE 540
SDTHAVQIAL MALKMMELSN EVMSPHGEPI KMRIGLHSGS VFAGVVGVKM PRYCLFGNNV 600
TLANKFESCS VPRKINVSPT TYRLLKDCPG FVFTPRSREE LPPNFPSDIP GICHFLDAYQ 660
HQGPNSKPWF QQKDAEDGNA NFLGKASGVD 690 |
Gene Ontology | GO:0008074; C:guanylate cyclase complex, soluble; IDA:RGD. GO:0005525; F:GTP binding; IDA:RGD. GO:0004383; F:guanylate cyclase activity; IDA:RGD. GO:0046982; F:protein heterodimerization activity; IDA:RGD. GO:0007263; P:nitric oxide mediated signal transduction; IDA:RGD. GO:0009635; P:response to herbicide; IEP:RGD. GO:0014070; P:response to organic cyclic compound; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |