UniProt Accession

 DC2L1_HUMAN; Q8TCX1; A8MVJ5; Q53F57; Q6PDB2; Q8IWA3; Q96B03; Q96J00; Q9Y370; Q9Y3S9 

Genbank Protein ID

 AY083346; AF151818; AK223432; AC011242; CH471053; CH471053; CH471053; BC006969; BC016324; BC040558; BC058823; AL050006 

Genbank Nucleotide ID

 AAL99216.1; AAD34055.1; BAD97152.1; AAY14702.1; EAX00289.1; EAX00290.1; EAX00291.1; AAH06969.1; AAH16324.1; AAH40558.1; AAH58823.1; CAB43233.1 

Protein Name

 Cytoplasmic dynein 2 light intermediate chain 1 

Protein Synonyms/Alias

 Dynein 2 light intermediate chain 

Gene Name

 DYNC2LI1 

Gene Synonyms/Alias

 D2LIC; LIC3; CGI-60 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
11	ETLWEIAKAEVEKRG	ubiquitination	[1]
151	KLGKTNAKAVSEMRQ	ubiquitination	[1]
330	VDEMRIQKDLELEQY	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis (By similarity). 

Sequence Annotation

  

Keyword

 Alternative splicing; Cell projection; Cilium; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Developmental protein; Dynein; Microtubule; Motor protein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 351 AA 

Protein Sequence

Gene Ontology

 GO:0045177; C:apical part of cell; ISS:BHF-UCL.
 GO:0005858; C:axonemal dynein complex; ISS:BHF-UCL.
 GO:0035085; C:cilium axoneme; ISS:BHF-UCL.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0030990; C:intraflagellar transport particle; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0031512; C:motile primary cilium; ISS:BHF-UCL.
 GO:0003774; F:motor activity; IEA:UniProtKB-KW.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
 GO:0042384; P:cilium assembly; IEA:Compara.
 GO:0007368; P:determination of left/right symmetry; IEA:Compara. 

Interpro

 IPR022780; Dynein_light_int_chain.
 IPR027417; P-loop_NTPase. 

Pfam

 PF05783; DLIC 

SMART

  

PROSITE

  

PRINTS