CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025435
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Parp3 
Protein Synonyms/Alias
  
Gene Name
 Parp3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
344KAIQTYLKQTGNSYRacetylation[1, 2]
344KAIQTYLKQTGNSYRubiquitination[3]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 533 AA 
Protein Sequence
MAPKRKASVQ TEGSKKRRQG TEEEDSFRST AEALRAAPAD NRVIRVDPSC PFSRNPGIQV 60
HEDYDCTLNQ TNIGNNNNKF YIIQLLEEGS RFFCWNRWGR VGEVGQSKMN HFTCLEDAKK 120
DFKKKFWEKT KNKWEERDRF VAQPNKYTLI EVQGEAESQE AVVKALSPQV YSGPVRTVVK 180
PCSLDPATQN LITNIFSKEM FKNAMTLMNL DVKKMPLGKL TKQQIARGFE ALEALEEAMK 240
NPTGDGQSLE ELSSCFYTVI PHNFGRSRPP PINSPDVLQA KKDMLLVLAD IELAQTLQAA 300
PGEEEEKVEE VPHPLDRDYQ LLRCQLQLLD SGESEYKAIQ TYLKQTGNSY RCPDLRHVWK 360
VNREGEGDRF QAHSKLGNRR LLWHGTNVAV VAAILTSGLR IMPHSGGRVG KGIYFASENS 420
KSAGYVTTMH CGGHQVGYMF LGEVALGKEH HITIDDPSLK SPPSGFDSVI ARGQTEPDPA 480
QDIELELDGQ PVVVPQGPPV QCPSFKSSSF SQSEYLIYKE SQCRLRYLLE IHL 533 
Gene Ontology
 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
 GO:0006471; P:protein ADP-ribosylation; IEA:InterPro. 
Interpro
 IPR012317; Poly(ADP-ribose)pol_cat_dom.
 IPR004102; Poly(ADP-ribose)pol_reg_dom.
 IPR008893; WGR_domain. 
Pfam
 PF00644; PARP
 PF02877; PARP_reg
 PF05406; WGR 
SMART
 SM00773; WGR 
PROSITE
 PS51060; PARP_ALPHA_HD
 PS51059; PARP_CATALYTIC 
PRINTS