UniProt Accession

 H7C5S6_HUMAN; H7C5S6 

Genbank Protein ID

 AC093668 

Genbank Nucleotide ID

  

Protein Name

 Leucine-rich repeat and WD repeat-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 LRWD1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
18	LSEHLDPKLLCRLTQ	ubiquitination	[1]
98	FLLPTLRKVNGKDAS	ubiquitination	[1]
128	RVTAHWEKFMATLGP	ubiquitination	[1]
148	KAQADFVKSAVRDVR	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 179 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp. 

Pfam

  

SMART

 SM00369; LRR_TYP 

PROSITE

 PS51450; LRR 

PRINTS