UniProt Accession

 E9Q197_MOUSE; E9Q197 

Genbank Protein ID

 AL591129 

Genbank Nucleotide ID

  

Protein Name

 Glyoxalase domain-containing protein 4 

Protein Synonyms/Alias

  

Gene Name

 Glod4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
52	CNGPYDGKWSKTMVG	acetylation	[1]
109	KLEWPLSKVAEGIFE	acetylation	[2]
109	KLEWPLSKVAEGIFE	succinylation	[2]
124	TEAPGGYKFYLQDRS	ubiquitination	[3]
140	SQSDPVLKVTLAVSD	ubiquitination	[3]
170	IYEQDEEKQRALLGY	acetylation	[1, 2]
170	IYEQDEEKQRALLGY	succinylation	[2]
209	IAFSCPQKELPDLED	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 279 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI. 

Interpro

 IPR025870; Glyoxalase-like_dom. 

Pfam

 PF12681; Glyoxalase_2 

SMART

  

PROSITE

  

PRINTS