| Tag | Content |
|---|
| CPLM ID | CPLM-005692 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium- and chloride-dependent glycine transporter 1 |
Protein Synonyms/Alias | GlyT-1; GlyT1; Solute carrier family 6 member 9 |
Gene Name | Slc6a9 |
Gene Synonyms/Alias | Glyt1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 635 | QRLKNATKPSRDWGP | ubiquitination | [1] | | 673 | VQPLHPDKAQIPIVG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission. |
Sequence Annotation | |
Keyword | Alternative promoter usage; Alternative splicing; Amino-acid transport; Complete proteome; Membrane; Neurotransmitter transport; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 692 AA |
Protein Sequence | MIGGDTRAAS AHPGMASAQG PVATPSPEQP FPGTTSVSLA RPVLRVWHGA HSSGLLPNLI 60
AQHSPAMAQN GAVPSEATKK DQNLTRGNWG NQIEFVLTSV GYAVGLGNVW RFPYLCYRNG 120
GGAFMFPYFI MLIFCGIPLF FMELSFGQFA SQGCLGVWRI SPMFKGVGYG MMVVSTYIGI 180
YYNVVICIAF YYFFSSMTHV LPWAYCNNPW NTPDCAGVLD ASNLTNGSRP AALSGNLSHL 240
FNYTLQRTSP SEEYWRLYVL KLSDDIGNFG EVRLPLLGCL GVSWVVVFLC LIRGVKSSGK 300
VVYFTATFPY VVLTILFVRG VTLEGAFTGI MYYLTPQWDK ILEAKVWGDA ASQIFYSLGC 360
AWGGLITMAS YNKFHNNCYR DSVIISITNC ATSVYAGFVI FSILGFMANH LGVDVSRVAD 420
HGPGLAFVAY PEALTLLPIS PLWSLLFFFM LILLGLGTQF CLLETLVTAI VDEVGNEWIL 480
QKKTYVTLGV AVAGFLLGIP LTSQAGIYWL LLMDNYAASF SLVVISCIMC VSIMYIYGHR 540
NYFQDIQMML GFPPPLFFQI CWRFVSPAII FFILIFTVIQ YRPITYNHYQ YPGWAVAIGF 600
LMALSSVICI PLYALFQLCR TDGDTLLQRL KNATKPSRDW GPALLEHRTG RYAPTTTPSP 660
EDGFEVQPLH PDKAQIPIVG SNGSSRFQDS RI 692 |
Gene Ontology | GO:0016021; C:integral to membrane; IC:MGI. GO:0005887; C:integral to plasma membrane; IEA:InterPro. GO:0005886; C:plasma membrane; IDA:MGI. GO:0015187; F:glycine transmembrane transporter activity; IDA:MGI. GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. GO:0005283; F:sodium:amino acid symporter activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |