UniProt Accession

 B7Z419_HUMAN; B7Z419 

Genbank Protein ID

 AC012173; AK296630 

Genbank Nucleotide ID

 BAH12405.1 

Protein Name

 Phosphomannomutase 2 

Protein Synonyms/Alias

 cDNA FLJ50559, highly similar to Phosphomannomutase 2 (EC 5.4.2.8) 

Gene Name

 PMM2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
24	IEFYELDKKENIRQK	acetylation	[1, 2]
77	HVENDGYKTIYFFGD	ubiquitination	[3]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 121 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0004615; F:phosphomannomutase activity; IEA:InterPro.
 GO:0019307; P:mannose biosynthetic process; IEA:InterPro. 

Interpro

 IPR023214; HAD-like_dom.
 IPR005002; PMM. 

Pfam

 PF03332; PMM 

SMART

  

PROSITE

  

PRINTS