CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032222
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase Chk2 
Protein Synonyms/Alias
  
Gene Name
 CHEK2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
255RDEYIMSKTLGSGACubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MSRESDVEAQ QSHGSSACSQ PHGSVTQSQG SSSQSQGISS SSTSTMPNSS QSSHSSSGTL 60
SSLETVSTQE LYSIPEDQEP EDQEPEEPTP APWARLWALQ DGFANLETES GHVTQSDLEL 120
LLSSDPPASA SQSAGIRECV NDNYWFGRDK SCEYCFDEPL LKRTDKYRTY SKKHFRIFRE 180
VGPKNSYIAY IEDHSGNGTF VNTELVGKGK RRPLNNNSEI ALSLSRNKVF VFFDLTVDDQ 240
SVYPKALRDE YIMSKTLGSG ACGEVKLAFE RKTCKKVAIK IISKRKFAIG SAREA 295 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR000253; FHA_dom.
 IPR011009; Kinase-like_dom.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA 
SMART
 SM00240; FHA 
PROSITE
 PS50006; FHA_DOMAIN 
PRINTS