| Tag | Content |
|---|
| CPLM ID | CPLM-014069 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 |
Protein Synonyms/Alias | Development and differentiation-enhancing factor-like 1 |
Gene Name | Asap3 |
Gene Synonyms/Alias | Ddefl1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 242 | SLSPFIDKLAASVHG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Promotes cell proliferation (By similarity). |
Sequence Annotation | DOMAIN 302 394 PH.
DOMAIN 425 550 Arf-GAP.
REPEAT 584 616 ANK 1.
REPEAT 620 649 ANK 2.
ZN_FING 440 463 C4-type. |
Keyword | ANK repeat; Coiled coil; Complete proteome; Cytoplasm; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 904 AA |
Protein Sequence | MPEQLSVAEF LAVTAEDLSS PAGAAAFAAK MPRCRGAALA REEALEGDQA ILQRIKKAVR 60
AIHSSGLGHV ETEEHYREAV EALGNSHLSQ NSHELSTGFL NLAVFTREVA ALFKNLVQNL 120
NNIVSFPLDS LMKGHLRDGR HDSKKHLEKA WKDYESKVAK LEKERDRARF PGGSHGVMSQ 180
DTQRERRVFQ LHMCEYLVKA GESQVKQGPD FLQSLIKFFH AQHNFFQDGW KAAQSLSPFI 240
DKLAASVHGL RQAQEEELHK LTQLRDSLRG MLHLESREDH PNRKNSGGGY SIHQHQGNKQ 300
FGTEKVGFLY KKSDGIRRVW QKRKCGVKYG CLTISHSMIN RPPVKLPLLT CQVRPNPEEK 360
RCFDLVTHNR TYHFHAEDEQ ECEAWVSVLQ NSKDEALSNA FHGEPSGGQW SWGTRLDTEP 420
HDLTNMLVAE VKSRPGNDRC CDCGAADPTW LSTNLGVLTC IQCSGVHREL GVRFSRIQSL 480
TLDLLGPSEL LLALNIGNSH FNEVMEAHLP SHGSPKPSAE SDMSSRRNYI VAKYVEHKFA 540
RHSTPDPQKL RTAICSRDLL SVLEAFANGQ DFGQLLPGPD GQAPGELALH LAIRVASHAS 600
LPIVDFLIQN GGHLDAKAAD GNTALHCAAL HGQLDCLKLL LRGRAPVGAV NDAGETALDI 660
ARNRQHKECE ELLEQAQAGT LAFPLHMDYH WGHSMEHGFD SEEEEEEEKH CPSKPPAQAC 720
WGSVRLDISN KTYETVATPG PATTQSQSED SPPPLPIKNS SRTIVLGRAG HCSGDRSDLP 780
SLRSESPEAL ENRSSPASSS SSLTSSVEPG GLSQAPSSPE EGLQESASIS RPGLASGTTS 840
AEVYLPVKFS SESTRSYRRG GRSLEDSPSA RQPLCSRRHI PVGLVEGDGS KIGVLPDSLQ 900
LLHD 904 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0008060; F:ARF GTPase activator activity; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |