CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009803
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ 
Protein Synonyms/Alias
 tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase; tRNA Cm32/Um32 methyltransferase 
Gene Name
 trmJ 
Gene Synonyms/Alias
 STM2545 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
241ASIEQQNKGK*****acetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA (By similarity). 
Sequence Annotation
 BINDING 114 114 S-adenosyl-L-methionine; via carbonyl
 BINDING 134 134 S-adenosyl-L-methionine; via amide
 BINDING 143 143 S-adenosyl-L-methionine; via amide  
Keyword
 Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 243 AA 
Protein Sequence
MLQNIRIVLV ETSHTGNMGS VARAMKTMGL TNLWLVNPLV KPDSQAIALA AGASDVIGNA 60
QIVDTLDEAL AGCSLVVGTS ARSRTLPWPM LDPRECGLKS VAEAANTPVA LVFGRERVGL 120
TNDELQKCHY HVAIAANPEY SSLNLAMAVQ VIAYEVRMAW LATQENGDAA DHEETPYPLV 180
DDLERFYGHL EQTLLSTGFI RENHPGQVMN KLRRLFTRAR PESQELNILR GILASIEQQN 240
KGK 243 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
 GO:0001510; P:RNA methylation; IEA:GOC.
 GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR004384; rRNA_MeTrfase_TrmH_1.
 IPR001537; SpoU_MeTrfase. 
Pfam
 PF00588; SpoU_methylase 
SMART
  
PROSITE
  
PRINTS