CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018721
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein FAM3C 
Protein Synonyms/Alias
 Interleukin-like EMT inducer 
Gene Name
 FAM3C 
Gene Synonyms/Alias
 ILEI; GS3786 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
112NVALANGKTGEVLDTubiquitination[1]
156TYDDGATKLNDEARRubiquitination[1]
193GGKGIKTKSPFEQHIubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition. 
Sequence Annotation
 DISULFID 58 86 By similarity.
 DISULFID 64 221 By similarity.  
Keyword
 Complete proteome; Cytoplasmic vesicle; Developmental protein; Disulfide bond; Oncogene; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 227 AA 
Protein Sequence
MRVAGAAKLV VAVAVFLLTF YVISQVFEIK MDASLGNLFA RSALDTAARS TKPPRYKCGI 60
SKACPEKHFA FKMASGAANV VGPKICLEDN VLMSGVKNNV GRGINVALAN GKTGEVLDTK 120
YFDMWGGDVA PFIEFLKAIQ DGTIVLMGTY DDGATKLNDE ARRLIADLGS TSITNLGFRD 180
NWVFCGGKGI KTKSPFEQHI KNNKDTNKYE GWPEVVEMEG CIPQKQD 227 
Gene Ontology
 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; NAS:UniProtKB.
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005125; F:cytokine activity; NAS:UniProtKB.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. 
Interpro
 IPR026101; FAM3. 
Pfam
  
SMART
  
PROSITE
  
PRINTS