CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025457
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G-protein signalling modulator 2 (AGS3-like, C. elegans) 
Protein Synonyms/Alias
  
Gene Name
 Gpsm2 
Gene Synonyms/Alias
 mCG_121182 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
155LGNVYHAKGKSFGCPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 679 AA 
Protein Sequence
MEGNLISMRE DHSFHVRYRM EASCLELALE GERLCKSGDC RAGVSFFEAA VQVGTEDLKT 60
LSAIYSQLGN AYFYLHDYAK ALEYHHHDLT LARTIGDQLG EAKASGNLGN TLKVLGNFDE 120
AIVCCQRHLD ISRELNDKVG EARALYNLGN VYHAKGKSFG CPGPQDTGEF PEDVRNALQA 180
AVDLYEENLS LVTALGDRAA QGRAFGNLGN THYLLGNFRD AVIAHEQRLL IAKEFGDKAA 240
ERRAYSNLGN AYIFLGEFET ASEYYKKTLL LARQLKDRAV EAQSCYSLGN TYTLLQDYEK 300
AIDYHLKHLA IAQELKDRIG EGRACWSLGN AYTALGNHDQ AMHFAEKHLE ISREVGDKSG 360
ELTARLNLSD LQMVLGLSYS TNNSMMSENI EIDGSLHGAG AKLGRRHSME NLELMKLTPE 420
KVPNWNSEIL AKQKPLIAKP SAKLLFVNRL KGKKYKSGSA CTKVLQDASN SVDHRAPRSQ 480
KKISSDTIGD EGFFDLLRRF QSNRMDDQRC HLQGNCRTTS TAAASATPKL MKAPSVSVVS 540
PNTDEFLDLL ASSQSRRLDD QRASFSNLPG LRLTKGNSPS VLERLMTNDK KEPDEDFFDI 600
LVKCQGSRLD DQRCAPPSAA TKGPTVPDED FFSLILRSQA KRMDEQRVLL QRDPNRDSEF 660
GLKELLQNNA LLEFKHSGK 679 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:MGI.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005092; F:GDP-dissociation inhibitor activity; IEA:InterPro.
 GO:0000132; P:establishment of mitotic spindle orientation; IMP:MGI.
 GO:0060487; P:lung epithelial cell differentiation; IMP:MGI.
 GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:InterPro. 
Interpro
 IPR024807; G_prot_signal_mod_2.
 IPR003109; GoLoco_motif.
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF02188; GoLoco
 PF00515; TPR_1
 PF13176; TPR_7 
SMART
 SM00390; GoLoco
 SM00028; TPR 
PROSITE
 PS50877; GOLOCO
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS