CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031247
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serpin B8 
Protein Synonyms/Alias
 cDNA FLJ57144, highly similar to Serpin B8 
Gene Name
 SERPINB8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
76KAWTNSEKLTKSKVQubiquitination[1]
81SEKLTKSKVQVFLPRubiquitination[1, 2]
90QVFLPRLKLEESYDLubiquitination[1]
114IDAFDEAKADFSGMSubiquitination[3]
124FSGMSTEKNVPLSKVubiquitination[1]
130EKNVPLSKVAHKCFVubiquitination[1, 2]
134PLSKVAHKCFVEVNEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 192 AA 
Protein Sequence
MLFKTNEEKK TVQMMFKEAK FKMGYADEVH TQVLELPYVE EELSMVILLP DDNTDLAVVE 60
KALTYEKFKA WTNSEKLTKS KVQVFLPRLK LEESYDLEPF LRRLGMIDAF DEAKADFSGM 120
STEKNVPLSK VAHKCFVEVN EEGTEAAAAT AVVRNSRCSR MEPRFCADHP FLFFIRHHKT 180
NCILFCGRFS SP 192 
Gene Ontology
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro. 
Interpro
 IPR023795; Protease_inhib_I4_serpin_CS.
 IPR023796; Serpin_dom.
 IPR000215; Serpin_fam. 
Pfam
 PF00079; Serpin 
SMART
 SM00093; SERPIN 
PROSITE
 PS00284; SERPIN 
PRINTS