| Tag | Content |
|---|
| CPLM ID | CPLM-005287 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RNA polymerase sigma-54 factor |
Protein Synonyms/Alias | |
Gene Name | rpoN |
Gene Synonyms/Alias | glnF; ntrA; b3202; JW3169 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 327 | RSNLQDAKWLIKSLE | acetylation | [1] | | 331 | QDAKWLIKSLESRND | acetylation | [1] | | 435 | IAAENPAKPLSDSKL | acetylation | [1] | | 441 | AKPLSDSKLTSLLSE | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC). |
Sequence Annotation | DNA_BIND 366 385 H-T-H motif (By similarity).
MOTIF 454 462 RPON box. |
Keyword | Arginine metabolism; Complete proteome; DNA-binding; DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome; Sigma factor; Transcription; Transcription regulation; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 477 AA |
Protein Sequence | MKQGLQLRLS QQLAMTPQLQ QAIRLLQLST LELQQELQQA LESNPLLEQI DTHEEIDTRE 60
TQDSETLDTA DALEQKEMPE ELPLDASWDT IYTAGTPSGT SGDYIDDELP VYQGETTQTL 120
QDYLMWQVEL TPFSDTDRAI ATSIVDAVDE TGYLTVPLED ILESIGDEEI DIDEVEAVLK 180
RIQRFDPVGV AAKDLRDCLL IQLSQFDKTT PWLEEARLII SDHLDLLANH DFRTLMRVTR 240
LKEDVLKEAV NLIQSLDPRP GQSIQTGEPE YVIPDVLVRK HNGHWTVELN SDSIPRLQIN 300
QHYASMCNNA RNDGDSQFIR SNLQDAKWLI KSLESRNDTL LRVSRCIVEQ QQAFFEQGEE 360
YMKPMVLADI AQAVEMHEST ISRVTTQKYL HSPRGIFELK YFFSSHVNTE GGGEASSTAI 420
RALVKKLIAA ENPAKPLSDS KLTSLLSEQG IMVARRTVAK YRESLSIPPS NQRKQLV 477 |
Gene Ontology | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW. GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW. GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |