CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042011
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HCG21296, isoform CRA_c 
Protein Synonyms/Alias
 Uncharacterized protein C4orf21 
Gene Name
 C4orf21 
Gene Synonyms/Alias
 hCG_21296 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1275FPSGQKIKSAYLPQRubiquitination[1]
1421GLYLRSQKIPLYEECubiquitination[1]
1772RKSIEQHKLGTNRTLubiquitination[1]
1781GTNRTLLKQVRVVGVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2104 AA 
Protein Sequence
MESQEFIVLY THQKMKKSKV WQDGILKITH LGNKAILYDD KGACLESLFL KCLEVKPGDD 60
LESDRYLITV EEVKVAGAIG IVKQNVNKEA PELNSRTFIS SGRSLGCQPS GLKRKFTGFQ 120
GPRQVPKKMV IMESGESAAS HEAKKTGPTI FSPFCSMPPL FPTVGKKDVN NILADPENIV 180
TYKNRERNAM DFSSVFSPSF QINPEVLCEE NYFCSPVNSG NKLSDSLLTN EPVKRDSLAS 240
HYSGVSQNIR SKAQILALLK SESSSSCEEL NSEMTEHFPQ KQPQGSLKIA TKPKYLIQQE 300
ECAEMKSTEN LYYQHQSENT MRNKSRWAMY LSSQSSPIHS STVDGNDTER KPKAQEDDVN 360
SNLKDLSLQK IIQFVETYAE ERKKYNVDQS VGNNDPSWNQ EVKLEIPSFN ESSSLQVTCS 420
SAENDGILSE SDIQEDNKIP FNQNDKGCIK GSVLIKENAQ EVNTCGTLEK EYEQSESSLP 480
ELKHLQIESS NNSRISDDIT DMISESKMDN ESLNSIHESL SNVTQPFLEV TFNLNNFETS 540
DTEEESQESN KISQDSESWV KDILVNDGNS CFQKRSENTN CEEIEGEHLP FLTSVSDKPT 600
VTFPVKETLP SQFCDKTYVG FDMGICKTEN TGKEIEEYSD TLSNFESFKW TDAVYGDNKE 660
DANKPIQEVR INYDFALPPN KSKGINMNLH IPHIQNQIAE NSNLFSEDAQ PQPFILGSDL 720
DKNDEHVLPS TSSSDNSVQL LNTNQNHYEC IALDKSNTHI SNSLFYPLGK KHLISKDTEA 780
HISEPEDLGK IRSPPPDHVE VETAREGKQY WNPRNSSELS GLVNTISILK SLCEHSTALD 840
SLEILKKKNT VFQQGTQQTY EPDSPPEVRK PFITVVSPKS PHLHKDSQQI LKEDEVELSE 900
PLQSVQFSSS GSKEETAFQA VIPKQIERKT CDPKPVEFQG HQVKGSATSG VMVRGHSSQL 960
GCSQFPDSTE YENFMTETPE LPSTCMQIDF LQVTSPEENI STLSPVSTFS LNSRDEDFMV 1020
EFSETSLKAR TLPDDLHFLN LEGMKKSRSL ENENLQRLSL LSRTQVPLIT LPRTDGPPDL 1080
DSHSYMINSN TYESSGSPML NLCEKSAVLS FSIEPEDQNE TFFSEESREV NPGDVSLNNI 1140
STQSKWLKYQ NTSQCNVATP NRVDKRITDG FFAEAVSGMH FRDTSERQSD AVNESSLDSV 1200
HLQMIKGMLY QQRQDFSSQD SVSRKKVLSL NLKQTSKTEE IKNVLGGSTC YNYSVKDLQE 1260
ISGSELCFPS GQKIKSAYLP QRQIHIPAVF QSPAHYKQTF TSCLIEHLNI LLFGLAQNLQ 1320
KALSKVDISF YTSLKGEKLK NAENNVPSCH HSQPAKLVMV KKEGPNKGRL FYTCDGPKAD 1380
RCKFFKWLED VTPGYSTQEG ARPGMVLSDI KSIGLYLRSQ KIPLYEECQL LVRKGFDFQR 1440
KQYGKLKKFT TVNPEFYNEP KTKLYLKLSR KERSSAYSKN DLWVVSKTLD FELDTFIACS 1500
AFFGPSSINE IEILPLKGYF PSNWPTNMVV HALLVCNAST ELTTLKNIQD YFNPATLPLT 1560
QYLLTTSSPT IVSNKRVSKR KFIPPAFTNV STKFELLSLG ATLKLASELI QVHKLNKDQA 1620
TALIQIAQMM ASHESIEEVK ELQTHTFPIT IIHGVFGAGK SYLLAVVILF FVQLFEKSEA 1680
PTIGNARPWK LLISSSTNVA VDRVLLGLLS LGFENFIRVG SVRKIAKPIL PYSLHAGSEN 1740
ESEQLKELHA LMKEDLTPTE RVYVRKSIEQ HKLGTNRTLL KQVRVVGVTC AACPFPCMND 1800
LKFPVVVLDE CSQITEPASL LPIARFECEK LILVGDPKQL PPTIQGSDAA HENGLEQTLF 1860
DRLCLMGHKP ILLRTQYRCH PAISAIANDL FYKGALMNGV TEIERSPLLE WLPTLCFYNV 1920
KGLEQIERDN SFHNVAEATF TLKLIQSLIA SGIAGSMIGV ITLYKSQMYK LCHLLSAVDF 1980
HHPDIKTVQV STVDAFQGAE KEIIILSCVR TRQVGFIDSE KRMNVALTRG KRHLLIVGNL 2040
ACLRKNQLWG RVIQHCEGRE DGLQHANQYE PQLNHLLKDY FEKQVEEKQK KKSEKEKSKD 2100
KSHS 2104 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR018838; DUF2439.
 IPR027417; P-loop_NTPase.
 IPR010666; Znf_GRF. 
Pfam
 PF10382; DUF2439
 PF06839; zf-GRF 
SMART
  
PROSITE
  
PRINTS