CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010301
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cation efflux system protein CusB 
Protein Synonyms/Alias
  
Gene Name
 cusB 
Gene Synonyms/Alias
 ylcD; b0574; JW0563 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
134RAAGFIDKVYPLTVGacetylation[1]
211IQTRFTLKAPIDGVIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Part of a cation efflux system that mediates resistance to copper and silver. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Copper; Copper transport; Ion transport; Reference proteome; Signal; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
MKKIALIIGS MIAGGIISAA GFTWVAKAEP PAEKTSTAER KILFWYDPMY PNTRFDKPGK 60
SPFMDMDLVP KYADEESSAS GVRIDPTQTQ NLGVKTATVT RGPLTFAQSF PANVSYNEYQ 120
YAIVQARAAG FIDKVYPLTV GDKVQKGTPL LDLTIPDWVE AQSEYLLLRE TGGTATQTEG 180
ILERLRLAGM PEADIRRLIA TQKIQTRFTL KAPIDGVITA FDLRAGMNIA KDNVVAKIQG 240
MDPVWVTAAI PESIAWLVKD ASQFTLTVPA RPDKTLTIRK WTLLPGVDAA TRTLQLRLEV 300
DNADEALKPG MNAWLQLNTA SEPMLLIPSQ ALIDTGSEQR VITVDADGRF VPKRVAVFQA 360
SQGVTALRSG LAEGEKVVSS GLFLIDSEAN ISGALERMRS ESATHAH 407 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005507; F:copper ion binding; IDA:EcoCyc.
 GO:0005375; F:copper ion transmembrane transporter activity; IGI:EcoCyc.
 GO:0006878; P:cellular copper ion homeostasis; IMP:EcoCyc.
 GO:0060003; P:copper ion export; IGI:EcoCyc.
 GO:0010273; P:detoxification of copper ion; IMP:EcoCyc.
 GO:0015679; P:plasma membrane copper ion transport; IGI:EcoCyc.
 GO:0010272; P:response to silver ion; IEP:EcoCyc. 
Interpro
 IPR006143; RND_pump_MFP. 
Pfam
  
SMART
  
PROSITE
  
PRINTS