CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010635
UniProt Accession
Genbank Protein ID
 U65593 
Genbank Nucleotide ID
Protein Name
 Voltage-gated potassium channel subunit beta-3 
Protein Synonyms/Alias
 K(+) channel subunit beta-3; Kv-beta-3 
Gene Name
 Kcnab3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
154DTCKATVKGYQWLKEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv2.2 but not Kv2.1. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Ion channel; Ion transport; Potassium; Potassium transport; Reference proteome; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
MSRGYGLIFS LKVVFTFLSL PHPPGLQGSL DRLQLEYVDI VFANRSDPNS PMEEIVRAMT 60
YVINQGLALY WGTSRWSAAE IMEAYSMARQ FNLIPPVCEQ AENHFFQREK VEMQLPELYH 120
KIGVGSVTWS PLACGLITSK YDGRVPDTCK ATVKGYQWLK EKVQSEEGKK QQARVMDLLP 180
TARQLGCTVG QLAIAWCLRS EGVSSVLLGV SSAEQLMEHL GSLQVLSQLT PQTVVEIDAL 240
LGNKSHSKK 249 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR005983; K_chnl_volt-dep_bsu_KCNAB.
 IPR005399; K_chnl_volt-dep_bsu_KCNAB-rel.
 IPR005402; K_chnl_volt-dep_bsu_KCNAB3.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
  
PRINTS
 PR01580; KCNAB3CHANEL.
 PR01577; KCNABCHANNEL.