CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014289
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 
Protein Synonyms/Alias
 G gamma-C; G-gamma-8 
Gene Name
 Gngt2 
Gene Synonyms/Alias
 Gng8; Gngt8 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
8MAQDLSEKELLRMEVacetylation[1]
8MAQDLSEKELLRMEVsuccinylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
 Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. 
Sequence Annotation
 MOD_RES 66 66 Cysteine methyl ester (By similarity).
 LIPID 66 66 S-farnesyl cysteine (By similarity).  
Keyword
 Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Prenylation; Reference proteome; Transducer. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 69 AA 
Protein Sequence
MAQDLSEKEL LRMEVEQLKK EVKNPRDLIS KTGKEIKDYV EAQAGTDPLL KGIPEDKNPF 60
KEKGTCVLS 69 
Gene Ontology
 GO:0005834; C:heterotrimeric G-protein complex; IEA:Compara.
 GO:0003924; F:GTPase activity; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR015898; G-protein_gamma-like_dom.
 IPR001770; Gprotein-gamma. 
Pfam
 PF00631; G-gamma 
SMART
 SM00224; GGL 
PROSITE
 PS50058; G_PROTEIN_GAMMA 
PRINTS
 PR00321; GPROTEING.