| Tag | Content |
|---|
| CPLM ID | CPLM-007488 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 2 subunit 2 |
Protein Synonyms/Alias | Eukaryotic translation initiation factor 2 subunit beta; eIF-2-beta |
Gene Name | eIF-2beta |
Gene Synonyms/Alias | eIF2b; CG4153 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 244 | IKGRFQPKQIENVLR | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This preinitiation complex mediates ribosomal recognition of a start codon during the scanning process of the leader region. |
Sequence Annotation | ZN_FING 260 284 C4-type (Potential).
MOD_RES 44 44 Phosphoserine.
MOD_RES 133 133 Phosphoserine.
MOD_RES 145 145 Phosphothreonine. |
Keyword | Complete proteome; Initiation factor; Metal-binding; Phosphoprotein; Protein biosynthesis; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 312 AA |
Protein Sequence | MDAEDGFDPT LLKKKKKKKT TFDLDAALGL EDDTKKEDPQ DEASAEGGAA AEEDNLDLES 60
FGKKKKKKKK PFNMDEIEAA IPSFGGDDVA ASEEPEEEEI NLDMDFSMAK KKKKSKKKEL 120
DELFADQADD DKSEDKENDE DNSSTWFGSD RDYTYDELLK RVFEIILDKN PDMAAGRKPK 180
FVMRPPQVLR VGTKKTSFAN FMDIAKTLHR LPKHLLDFLL AELGTSGSMD GNQQLIIKGR 240
FQPKQIENVL RRYIKEYVTC HTCRSPETIL QKDTRLFFLQ CESCGSRCSV ASIKSGFQAV 300
TGKRAAIRAK TT 312 |
Gene Ontology | GO:0005829; C:cytosol; ISS:FlyBase. GO:0005850; C:eukaryotic translation initiation factor 2 complex; ISS:FlyBase. GO:0005875; C:microtubule associated complex; IDA:FlyBase. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0003743; F:translation initiation factor activity; ISS:FlyBase. GO:0016199; P:axon midline choice point recognition; IMP:FlyBase. GO:0000022; P:mitotic spindle elongation; IMP:FlyBase. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |