CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043480
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cirhin 
Protein Synonyms/Alias
  
Gene Name
 CIRH1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
10ADHLLHLKTKGPENIubiquitination[1]
52EHDNISLKRVSKMPAubiquitination[1, 2, 3]
205AQLPPPIKKKKFGT*ubiquitination[2, 4]
206QLPPPIKKKKFGT**ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 211 AA 
Protein Sequence
KNADHLLHLK TKGPENIICS CISPCGSWIA YSTVSRFFLY RLNYEHDNIS LKRVSKMPAF 60
LRSALQILFS EDSTKLFVAS NQGALHIVQL SGGSFKHLHA FQPQSGTVEA MCLLAVSPDG 120
NWLAASGTSA GVHVYNVKQL KLHCTVPAYN FPVTAMAIAP NTNNLVIAHS DQQPLLFMDL 180
LDERTLVAVE RPLDDIIAQL PPPIKKKKFG T 211 
Gene Ontology
  
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
  
PRINTS