UniProt Accession

 STX10_HUMAN; O60499; A6NC41; Q6IAP4; Q96AE8 

Genbank Protein ID

 AF035531; CR457110; AC011446; BC017237 

Genbank Nucleotide ID

 AAC05087.1; CAG33391.1; AAH17237.1 

Protein Name

 Syntaxin-10 

Protein Synonyms/Alias

 Syn10 

Gene Name

 STX10 

Gene Synonyms/Alias

 SYN10 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
126	NREILAGKPAAQKSP	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. 

Sequence Annotation

 DOMAIN 157 219 t-SNARE coiled-coil homology.
 MOD_RES 108 108 Phosphoserine.
 MOD_RES 110 110 Phosphothreonine.
 MOD_RES 134 134 Phosphoserine.
 MOD_RES 140 140 Phosphoserine.
 MOD_RES 143 143 Phosphoserine.  

Keyword

 3D-structure; Alternative splicing; Coiled coil; Complete proteome; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 249 AA 

Protein Sequence

Gene Ontology

 GO:0000139; C:Golgi membrane; TAS:ProtInc.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0048193; P:Golgi vesicle transport; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB. 

Interpro

 IPR015260; Syntaxin-6_N.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 

Pfam

 PF05739; SNARE
 PF09177; Syntaxin-6_N 

SMART

 SM00397; t_SNARE 

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS