| Tag | Content |
|---|
| CPLM ID | CPLM-015060 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Diacylglycerol kinase beta |
Protein Synonyms/Alias | DAG kinase beta; Diglyceride kinase beta; DGK-beta |
Gene Name | Dgkb |
Gene Synonyms/Alias | Kiaa0718 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 444 | LLVFVNPKSGGKQGE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Exhibits high phosphorylation activity for long-chain diacylglycerols (By similarity). |
Sequence Annotation | DOMAIN 148 183 EF-hand 1.
DOMAIN 193 228 EF-hand 2.
DOMAIN 432 566 DAGKc.
ZN_FING 243 293 Phorbol-ester/DAG-type 1.
ZN_FING 308 357 Phorbol-ester/DAG-type 2. |
Keyword | Alternative splicing; ATP-binding; Calcium; Complete proteome; Cytoplasm; Kinase; Metal-binding; Nucleotide-binding; Reference proteome; Repeat; Transferase; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 802 AA |
Protein Sequence | MTNQEKWAHL SPSEFSQLQK YAEYSTKKLK DVLEEFHGNG VLAKYNPEGK QDILNQTIDF 60
EGFKLFMKTF LEAELPDDFT AHLFMSFSNK FPHSSPNVKS KPALLSGGLR MNKGAITPPR 120
SSPANTCSPE VIHLKDIVCY LSLLERGRPE DKLEFMFRLY DTDGNGFLDS SELENIIGQM 180
MHVAEYLEWD VTELNPILHE MMEEIDYDRD GTVSLEEWIQ GGMTTIPLLV LLGLENNVKD 240
DGQHVWRLKH FNKPAYCNLC LNMLIGVGKQ GLCCSFCKYT VHERCVARAP PSCIKTYVKS 300
KKNTDVMHHY WVEGNCPTKC DKCHKTVKCY QGLTGLHCVW CQTTLHNKCA SHLKPECDCG 360
PLKDHILPPT TICPVVLTMP SAGASVPEER QSTAKKEKSS SQQPNKATDK NKMQRANSVT 420
MDGQGLQITP VPGTHPLLVF VNPKSGGKQG ERIYRKFQYL LNPRQVYSLS GNGPMPGLHF 480
FRDVPDFRVL ACGGDGTVGW ILDCIEKANV VKHPPVAILP LGTGNDLARC LRWGGGYEGE 540
NLMKILKDIE SSTEIMLDRW KFEVTPNDKD EKGDPVPYSI INNYFSIGVD ASIAHRFHIM 600
REKHPEKFNS RMKNKFWYFE FGTSETFSAT CKKLHESVEI ECDGVQIDLI NISLEGIAIL 660
NIPSMHGGSN LWGESKKKRS HRRIEKKGSD KRPTLTDAKE LKFASQDLSD QLLEVVGLEG 720
AMEMGQIYTG LKSAGRRLAQ CSSVVIRTSK SLPMQIDGEP WMQTPCTIKI THKNQAPMLM 780
GPPPKTGLFC SLIKRTRNRS KE 802 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; IDA:MGI. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0004143; F:diacylglycerol kinase activity; IDA:MGI. GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |