UniProt Accession

 ARL8A_MOUSE; Q8VEH3; Q99KS1; Q9CTB0 

Genbank Protein ID

 AB185207; BC004035; BC018479; AK004080 

Genbank Nucleotide ID

 BAD30091.1; AAH04035.1; AAH18479.1; BAB23160.1 

Protein Name

 ADP-ribosylation factor-like protein 8A 

Protein Synonyms/Alias

 ADP-ribosylation factor-like protein 10B; Novel small G protein indispensable for equal chromosome segregation 2 

Gene Name

 Arl8a 

Gene Synonyms/Alias

 Arl10b; Gie2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
62	FNMRKITKGNVTIKL	ubiquitination	[1]
68	TKGNVTIKLWDIGGQ	ubiquitination	[1]
141	LAGALDEKELIEKMN	ubiquitination	[1]
146	DEKELIEKMNLSAIQ	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity). 

Sequence Annotation

 NP_BIND 29 35 GTP (By similarity).
 NP_BIND 71 75 GTP (By similarity).
 NP_BIND 130 133 GTP (By similarity).  

Keyword

 Cell cycle; Cell division; Chromosome partition; Complete proteome; Endosome; GTP-binding; Lysosome; Membrane; Mitosis; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 186 AA 

Protein Sequence

Gene Ontology

 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
 GO:0030496; C:midbody; IEA:Compara.
 GO:0051233; C:spindle midzone; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 

Pfam

 PF00025; Arf 

SMART

 SM00177; ARF 

PROSITE

 PS51417; ARF 

PRINTS

 PR00328; SAR1GTPBP.