| Tag | Content |
|---|
| CPLM ID | CPLM-013779 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Scavenger receptor class F member 1 |
Protein Synonyms/Alias | Acetyl LDL receptor; Scavenger receptor expressed by endothelial cells 1 protein; SREC-I |
Gene Name | Scarf1 |
Gene Synonyms/Alias | Kiaa0149; Srec |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 731 | KVKSAIPKPLRRSLG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein (By similarity). Plays a role in the regulation of neurite-like outgrowth. |
Sequence Annotation | DOMAIN 56 90 EGF-like 1.
DOMAIN 98 133 EGF-like 2.
DOMAIN 163 193 EGF-like 3.
DOMAIN 217 251 EGF-like 4.
DOMAIN 304 341 EGF-like 5.
DOMAIN 353 384 EGF-like 6.
CARBOHYD 291 291 N-linked (GlcNAc...) (Potential).
DISULFID 60 72 By similarity.
DISULFID 66 78 By similarity.
DISULFID 80 89 By similarity.
DISULFID 102 114 By similarity.
DISULFID 108 121 By similarity.
DISULFID 123 132 By similarity.
DISULFID 166 174 By similarity.
DISULFID 168 181 By similarity.
DISULFID 183 192 By similarity.
DISULFID 221 232 By similarity.
DISULFID 225 239 By similarity.
DISULFID 241 250 By similarity. |
Keyword | Cell adhesion; Complete proteome; Disulfide bond; EGF-like domain; Glycoprotein; Membrane; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 820 AA |
Protein Sequence | MLAAMGLELV FSLLLLWTQG TQGSTLDPAG QHVCKGSSPS ELQCCPGWRQ KDQECTIPIC 60
EGPDACRKEE VCVKPGLCRC KPGFFGAQCS SRCPGQYWGH DCRETCPCHP RGQCEPATGD 120
CQCQPNYWGR LCEFPCTCGP HGQCDPKTGL CHCDPGWWSP TCRRPCQCNP ASRCDQATGT 180
CVCPPGWWGR RCSFSCNCHT SPCMQDSGRC VCLPGWWGPE CSRKCQCVRG QCSVTSGHCS 240
CPPGFHGIRC ELPCNPGHYG AQCKESCGHC ELNATCSPVT GNCESCKPGW NGTQCKQPCP 300
AGTFGERCTG QCPRCRLGEP CQAETGHCQH CDPGWLGHRC ENPCPLGTFG KGCSSTCPAC 360
AQGTCDAVTG ECVCSAGYWG TSCNSSCPAG FHGNNCSMPC QCPEGLCHPV SGTCQLGRHG 420
KNALIVGILV PLLLLLMGIV CCAYCCSGTR LDPKDRPERN GAAFFRMKQQ VWGALTNLGS 480
ALPCGSLSNY KLPWVTVSHH DPEVPFNHSF IEPPSAGWAS DDSFSSDPDS GEEDEAHAYF 540
VPPREEMVPM AQEESPEASL PGGSFPPPED ASTPFPIPRT SSLARAKRPS VSFAEGTKFA 600
PQNGRSSGDL SSPIRKPKRL SRGAQPRPEG QEAEESTGPE QVNTEEDAPT ATSSGDPATS 660
HGQLPPGSQM VAECAETTDG GIQESSGSVA TIYMLAGTPQ KPEGPVWSVF RRLGNYQKDQ 720
MDPKVKSAIP KPLRRSLGRN QASAGSAPGA VLSQAMESTA VRPEETPRGL GDGIESSGTV 780
QEPDAGGSSL EQDSQKQAEE KEQEEPLYEN VVPMSVPPQH 820 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0030169; F:low-density lipoprotein particle binding; IEA:Compara. GO:0005044; F:scavenger receptor activity; IEA:Compara. GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. GO:0016358; P:dendrite development; IDA:MGI. GO:0016322; P:neuron remodeling; IMP:UniProtKB. GO:0048680; P:positive regulation of axon regeneration; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |