UniProt Accession

 RISA_YEAST; P38145; D6VQQ3 

Genbank Protein ID

 Z21621; X70529; Z36125; BK006936 

Genbank Nucleotide ID

 CAA79745.1; CAA49920.1; CAA85219.1; DAA07373.1 

Protein Name

 Riboflavin synthase 

Protein Synonyms/Alias

 RS 

Gene Name

 RIB5 

Gene Synonyms/Alias

 YBR256C; YBR1724 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
75	GISPETIKRSNVASW	ubiquitination	[1]
138	LRDQEYFKYIVEKGF	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Catalyzes the dismutation of two molecules of 6,7- dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. 

Sequence Annotation

 REPEAT 1 103 Lumazine-binding 1.
 REPEAT 104 205 Lumazine-binding 2.
 REGION 87 91 Lumazine binding (Probable).
 REGION 189 193 Lumazine binding (Probable).
 MOD_RES 95 95 Phosphoserine.  

Keyword

 Complete proteome; Phosphoprotein; Reference proteome; Repeat; Riboflavin biosynthesis; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 238 AA 

Protein Sequence

Gene Ontology

 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0004746; F:riboflavin synthase activity; IDA:SGD.
 GO:0009231; P:riboflavin biosynthetic process; IMP:SGD. 

Interpro

 IPR023366; ATPase_F1/A1-cplx_a_su_N.
 IPR001783; Lumazine-bd.
 IPR026017; Lumazine-bd_dom.
 IPR017938; Riboflavin_synthase-like_b-brl. 

Pfam

 PF00677; Lum_binding 

SMART

  

PROSITE

 PS51177; LUMAZINE_BIND 

PRINTS