CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031069
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chitobiosyldiphosphodolichol beta-mannosyltransferase 
Protein Synonyms/Alias
 cDNA FLJ61145, highly similar to Chitobiosyldiphosphodolichol beta-mannosyltransferase (EC 2.4.1.142) 
Gene Name
 ALG1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
72LLAKWYEKFFGRLSHubiquitination[1]
106RAVTVYDKPASFFKEubiquitination[1, 2, 3]
112DKPASFFKETPLDLQubiquitination[1, 2, 3]
125LQHRLFMKLGSMHSPubiquitination[2]
284PVCAVNFKCLHELVKubiquitination[4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 353 AA 
Protein Sequence
MYLLWKLMWR EPGAYIFLQN PPGLPSIAVC WFVGCLCGSK LVIDWHNYGY SIMGLVHGPN 60
HPLVLLAKWY EKFFGRLSHL NLCVTNAMRE DLADNWHIRA VTVYDKPASF FKETPLDLQH 120
RLFMKLGSMH SPFRARSEPE DPVTERSAFT ERDAGSGLVT RLRERPALLV SSTSWTEDED 180
FSILLAALEK FEQLTLDGHN LPSLVCVITG KGPLREYYSR LIHQKHFQHI QVCTPWLEAE 240
DYPLLLGSAD LGVCLHTSSS GLDLPMKVVD MFGCCLPVCA VNFKCLHELV KHEENGLVFE 300
DSEELAAQLQ MLFSNFPDPA GKLNQFRKNL RESQQLRWDE SWVQTVLPLV MDT 353 
Gene Ontology
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW. 
Interpro
 IPR026051; ALG1-like. 
Pfam
  
SMART
  
PROSITE
  
PRINTS