| Tag | Content |
|---|
| CPLM ID | CPLM-020005 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-splicing factor SYF1 |
Protein Synonyms/Alias | Adapter protein ATH-55; XPA-binding protein 2 |
Gene Name | Xab2 |
Gene Synonyms/Alias | Ath55; Syf1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 420 | DARVILEKATKVNFK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (By similarity). |
Sequence Annotation | REPEAT 15 47 HAT 1.
REPEAT 48 80 HAT 2.
REPEAT 90 122 HAT 3.
REPEAT 124 158 HAT 4.
REPEAT 160 192 HAT 5.
REPEAT 198 230 HAT 6.
REPEAT 235 268 HAT 7.
REPEAT 270 305 HAT 8.
REPEAT 369 407 HAT 9.
REPEAT 498 530 HAT 10.
REPEAT 532 566 HAT 11.
REPEAT 571 605 HAT 12.
REPEAT 643 677 HAT 13.
REPEAT 679 713 HAT 14.
MOD_RES 420 420 N6-acetyllysine (By similarity).
MOD_RES 851 851 Phosphoserine (By similarity). |
Keyword | Acetylation; Complete proteome; DNA damage; DNA repair; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Spliceosome; Transcription. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 855 AA |
Protein Sequence | MVVMARVPRP ERPDLVFEEE DLPYEEEIMR NQFSVKCWLR YIEFKQGAPK PRLNQLYERA 60
LKLLPCSYKL WYRYLKARRA QVKHRCVTDP AYEDVNNCHE RAFVFMHKMP RLWLDYCQFL 120
MDQGRVTHTR RTFDRALRAL PITQHSRIWP LYLRFLRSHP LPETAVRGYR RFLKLSPESA 180
EEYIEYLKSS DRLDEAAQRL ATVVNDERFV SKAGKSNYQL WHELCDLISQ NPDKVQSLNV 240
DAIIRGGLTR FTDQLGKLWC SLADYYIRSG HFEKARDVYE EAIRTVMTVR DFTQVFDSYA 300
QFEESMIAAK METASELGRE EEDDVDLELR LARFEQLISR RPLLLNSVLL RQNPHHVHEW 360
HKRVALHQGR PREIINTYTE AVQTVDPFKA TGKPHTLWVA FAKFYEDNGQ LDDARVILEK 420
ATKVNFKQVD DLASVWCQCG ELELRHENYD EALKLLRKAT ALPARRAEYF DGSEPVQNRV 480
YKSLKVWSML ADLEESLGTF QSTKAVYDRI LDLRIATPQI VINYAMFLEE HKYFEESFKA 540
YERGISLFKW PNVSDIWSTY LTKFISRYGG RKLERARDLF EQALDGCPPK YAKTLYLLYA 600
QLEEEWGLAR HAMAVYDRAT RAVEPAQQYD MFNIYIKRAA EIYGVTHTRG IYQKAIEVLS 660
DEHAREMCLR FADMECKLGE IDRARAIYSF CSQICDPRTT GAFWQTWKDF EVRHGNEDTI 720
REMLRIRRSV QATYNTQVNF MASQMLKVSG SATGTVSDLA PGQSGMDDMK LLEQRAEQLA 780
AEAERDQPPR AQSKIFFVRS DASREELAEL AQQANPEEIQ LGEDEDEDEM DLEPNEVRLE 840
QQSVPAAVFG SLKED 855 |
Gene Ontology | GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara. GO:0001824; P:blastocyst development; IEA:Compara. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB. GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |