CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042956
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dehydrogenase/reductase SDR family member 7 
Protein Synonyms/Alias
  
Gene Name
 DHRS7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
98ENGNLKEKDILVLPLubiquitination[1]
118GSHEAATKAVLQEFGubiquitination[2]
258NNGDQSHKMTTSRCVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 399 AA 
Protein Sequence
XLWLLVLCAL LLLLVQLLRF LRADGDLTLL WAEWQGRRPE WELTDMVVWV TGASSGIGEE 60
LAYQLSKLGV SLVLSARRVH ELERVKRRCL ENGNLKEKDI LVLPLDLTDT GSHEAATKAV 120
LQEFGRIDIL VNNGGMSQRS LCMDTSLDVY RKLIELNYLG TVSLTKCVLP HMIERKQGKI 180
VTVNSILGII SVPLSIGYCA SKHALRGFFN GLRTELATYP GIIVSNICPG PVQSNIVENS 240
LAGEVTKTIG NNGDQSHKMT TSRCVRLMLI SMANDLKEVW ISEQPFLLVT YLWQYMPTWA 300
WWITNKMGKK RIENFKSGVV RPISKFLNSM YQSCRKVQNF PVFKKLSGWV QWLMSVIPAL 360
WEAKADHLRP GVQDQPGQHS ETPSLLKIQK VAGHGGACL 399 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0055114; P:oxidation-reduction process; IEA:GOC. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.