UniProt Accession

 YPT32_YEAST; P51996; D6VTU5 

Genbank Protein ID

 X72834; U33754; Z72732; AY558506; BK006941 

Genbank Nucleotide ID

 CAA51355.1; AAC49495.1; CAA96926.1; AAS56832.1; DAA07906.1 

Protein Name

 GTP-binding protein YPT32/YPT11 

Protein Synonyms/Alias

 Rab GTPase YPT32 

Gene Name

 YPT32 

Gene Synonyms/Alias

 YPT11; YGL210W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
200	MGSNGAPKGPTISLT	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Required for protein transport through the secretory pathway. Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment. Mediates the proper polarized localization of SEC2, a GEF for SEC4, but does not alter the exchange activity of SEC2 on SEC4. Plays a role in autophagy. 

Sequence Annotation

 NP_BIND 20 27 GTP (By similarity).
 NP_BIND 68 72 GTP (By similarity).
 NP_BIND 126 129 GTP (By similarity).
 MOTIF 42 50 Effector region (Probable).
 LIPID 221 221 S-geranylgeranyl cysteine (By
 LIPID 222 222 S-geranylgeranyl cysteine (By  

Keyword

 3D-structure; Autophagy; Complete proteome; Exocytosis; Golgi apparatus; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 222 AA 

Protein Sequence

Gene Ontology

 GO:0005768; C:endosome; IDA:SGD.
 GO:0005794; C:Golgi apparatus; IDA:SGD.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IDA:SGD.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0034498; P:early endosome to Golgi transport; IGI:SGD.
 GO:0006887; P:exocytosis; IMP:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.