| Tag | Content |
|---|
| CPLM ID | CPLM-013603 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acyl-coenzyme A amino acid N-acyltransferase 2 |
Protein Synonyms/Alias | |
Gene Name | Acnat2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | TATVKDEKENLFQSK | acetylation | [1] | | 47 | KENLFQSKAFYKANE | acetylation | [1] | | 405 | HSWREIQKFFRQHLL | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Acyltransferase which efficiently conjugates very long- chain and long-chain fatty acids to taurine. Shows no conjugation activity in the presence of glycine (By similarity). |
Sequence Annotation | MOTIF 416 418 Microbody targeting signal.
ACT_SITE 234 234 Charge relay system (By similarity).
ACT_SITE 327 327 Charge relay system (By similarity).
ACT_SITE 361 361 Charge relay system (By similarity). |
Keyword | Acyltransferase; Complete proteome; Fatty acid metabolism; Lipid metabolism; Peroxisome; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 418 AA |
Protein Sequence | MLQLIATPSN ALADEPVSIR AIGLPPSQIV TITATVKDEK ENLFQSKAFY KANEAGEVDL 60
EQASALGGDY VGVHPMGLFC CLKPKRAFQR LIKKDVMNSP LCICLDLYDS VCWLETVRIP 120
PKASQIVHRW FAGPGVKREQ IREGRVRGAL FLPPGKGPFP GIIDLFGSIG GLVEFRASLL 180
ASRGFAVLAL AYFAYEDLPK VLLEEDLDYF EEAANFLLAH PKIQQPGIGV ISVSKGAEIG 240
LAMACYLKQV VATVCINGPS AIFDFPLKYR DLVVTPMRLA FEKIQFHGSG AACFRHCWDP 300
QNMLNPPKIL PVEKAQGKIL FIVGENDQCL ASKLHAQRAM DRLRSHGRSS GRMLAYPGAG 360
HLIEPPYSPF CFACWDSVLG KPMLWGGDPI AHAAAQVHSW REIQKFFRQH LLQSGGKL 418 |
Gene Ontology | GO:0005777; C:peroxisome; ISS:UniProtKB. GO:0016410; F:N-acyltransferase activity; ISS:UniProtKB. GO:0016790; F:thiolester hydrolase activity; IEA:InterPro. GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro. GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |