CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040201
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol 3-kinase regulatory subunit gamma 
Protein Synonyms/Alias
  
Gene Name
 PIK3R3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
124SREEVNDKLRDMPDGubiquitination[1]
201YNPKLDVKLMYPVSRubiquitination[1]
216YQQDQLVKEDNIDAVubiquitination[1]
226NIDAVGKKLQEYHSQubiquitination[1]
284HTQEQHSKEYIERFRubiquitination[1]
308RIMMNYDKLKSRLGEubiquitination[1]
320LGEIHDSKMRLEQDLubiquitination[1]
340DNREIDKKMNSIKPDubiquitination[1]
345DKKMNSIKPDLIQLRubiquitination[1]
421AEDLLYGKPDGAFLIubiquitination[1]
434LIRESSKKGCYACSVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MGPSRLVRGP RPQGMRSPYR RPGMGWPRPR FPRMFKCSRR RYQQGLRGRT ASSAAINPAT 60
RAMGINNTHT DTTIVWIFPP QALPPKPPKP MTSAVPNGMK DSSVSLQDAE WYWGDISREE 120
VNDKLRDMPD GTFLVRDAST KMQGDYTLTL RKGGNNKLIK IYHRDGKYGF SDPLTFNSVV 180
ELINHYHHES LAQYNPKLDV KLMYPVSRYQ QDQLVKEDNI DAVGKKLQEY HSQYQEKSKE 240
YDRLYEEYTR TSQEIQMKRT AIEAFNETIK IFEEQCHTQE QHSKEYIERF RREGNEKEIE 300
RIMMNYDKLK SRLGEIHDSK MRLEQDLKNQ ALDNREIDKK MNSIKPDLIQ LRKIRDQHLV 360
WLNHKGVRQK RLNVWLGIKN EDADENYFIN EEDENLPHYD EKTWFVEDIN RVQAEDLLYG 420
KPDGAFLIRE SSKKGCYACS VVADGEVKHC VIYSTARGYG FAEPYNLYSS LKELVLHYQQ 480
TSLVQHNDSL NVRLAYPVHA QMPSLCR 507 
Gene Ontology
 GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
 GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
 GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; IEA:GOC. 
Interpro
 IPR001720; PI3kinase_P85.
 IPR000980; SH2. 
Pfam
 PF00017; SH2 
SMART
 SM00252; SH2 
PROSITE
 PS50001; SH2 
PRINTS
 PR00678; PI3KINASEP85.
 PR00401; SH2DOMAIN.