CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005683
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Single-stranded-DNA-specific exonuclease RecJ 
Protein Synonyms/Alias
  
Gene Name
 recJ 
Gene Synonyms/Alias
 STM3042 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
346EALILCEKLERSSETacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Single-stranded-DNA-specific exonuclease. Required for many types of recombinational events, although the stringency of the requirement for RecJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available. 
Sequence Annotation
  
Keyword
 Complete proteome; Exonuclease; Hydrolase; Nuclease; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 577 AA 
Protein Sequence
MKQQRQLRRR EADETAELPA DLPPLLRRLY ASRGVRSARE LERSVKGMLP WQQLSGIDNA 60
VEILYNAFRE GTRIIVVGDF DADGATSTAL SVLGMRALGC DNISYLVPNR FEDGYGLSPE 120
VVDQAKARGA QLIVTVDNGI SSHAGVAHAK TLGIPVIVTD HHLPGDTLPD AEAIINPNLR 180
DCEFPSKSLA GVGVAFYLML ALRTFLRDKG WFDERNIAPP NLAELLDLVA LGTVADVVPL 240
DANNRILTWQ GLSRIRAGKC RPGIKALLEI SNRDPQQLAA SDLGFALGPR LNAAGRLDDM 300
SVGVALLLCD NLGEARVLAS ELDALNQTRK EIEQGMQAEA LILCEKLERS SETLPGGLAM 360
YHPEWHQGVV GILASRIKER FHRPVIAFAP AGDGTLKGSG RSIQGLHMRD ALERLDTLYP 420
DLMIKFGGHA MAAGLSLEEH KFEQFQQRFG ELVTEWLDPA LLQGEVISDG PLSAAEMSME 480
VAQLLRDAGP WGQMFPEPLF DGRFRLLQQR LVGERHLKVM VEPVGGGPLL DGIAFNIDTT 540
CWPDNGVREV ELAYKLDINE FRGNRSLQII IDDIWPL 577 
Gene Ontology
 GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
 GO:0030145; F:manganese ion binding; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006310; P:DNA recombination; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR003156; Pesterase_DHHA1.
 IPR001667; Pesterase_RecJ.
 IPR004610; RecJ. 
Pfam
 PF01368; DHH
 PF02272; DHHA1 
SMART
  
PROSITE
  
PRINTS