CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041443
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 FERM domain-containing protein 6 
Protein Synonyms/Alias
  
Gene Name
 FRMD6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
476DDIRLYQKDFLRIAGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 545 AA 
Protein Sequence
MELSQKLYKY CPKEWKKEAS KGIDQFGPPM IIHFRVQYYV ENGRLISDRA ARYYYYWHLR 60
KQVLHSQCVL REEAYFLLAA FALQADLGNF KRNKHYGKYF EPEAYFPSWV VSKRGKDYIL 120
KHIPNMHKDQ FALTASEAHL KYIKEAVRLD DVAVHYYRLY KDKREIEASL TLGLTMRGIQ 180
IFQNLDEEKQ LLYDFPWTNV GKLVFVGKKF EILPDGLPSA RKLIYYTGCP MRSRHLLQLL 240
SNSHRLYMNL QPVLRHIRKL EENEEKKQYR ESYISDNLDL DMDQLEKRSR ASGSSAGSMK 300
HKRLSRHSTA SHSSSHTSGI EADTKPRDTG PEDSYSSSAI HRKLKTCSSM TSHGSSHTSG 360
VESGGKDRLE EDLQDDEIEM LVDDPRDLEQ MNEESLEVSP DMCIYITEDM LMSRKLNGHS 420
GLIVKEIGSS TSSSSETVVK LRGQSTDSLP QTICRKPKTS TDRHSLSLDD IRLYQKDFLR 480
IAGLCQDTAQ SYTFGCGHEL DEEGLYCNSC LAQQCINIQD AFPVKRTSKY FSLDLTHDEV 540
PEFVV 545 
Gene Ontology
 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:HPA. 
Interpro
 IPR019749; Band_41_domain.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR000299; FERM_domain.
 IPR018980; FERM_PH-like_C.
 IPR011993; PH_like_dom. 
Pfam
 PF09380; FERM_C
 PF00373; FERM_M 
SMART
 SM00295; B41 
PROSITE
 PS50057; FERM_3 
PRINTS