CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023344
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasome-associated protein ECM29 homolog 
Protein Synonyms/Alias
  
Gene Name
 CG8858 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
305KLLQYLIKCRGKSINacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 REPEAT 6 29 HEAT 1.
 REPEAT 30 67 HEAT 2.
 REPEAT 130 167 HEAT 3.
 REPEAT 226 263 HEAT 4.
 REPEAT 294 330 HEAT 5.
 REPEAT 334 354 HEAT 6.
 REPEAT 355 395 HEAT 7.
 REPEAT 459 496 HEAT 8.
 REPEAT 498 523 HEAT 9.
 REPEAT 524 561 HEAT 10.
 REPEAT 565 602 HEAT 11.
 REPEAT 685 722 HEAT 12.
 REPEAT 776 813 HEAT 13.
 REPEAT 843 882 HEAT 14.
 REPEAT 938 975 HEAT 15.
 REPEAT 980 1018 HEAT 16.
 REPEAT 1118 1155 HEAT 17.
 REPEAT 1159 1196 HEAT 18.
 REPEAT 1271 1309 HEAT 19.
 REPEAT 1313 1350 HEAT 20.
 REPEAT 1378 1415 HEAT 21.
 REPEAT 1416 1457 HEAT 22.
 REPEAT 1497 1534 HEAT 23.
 REPEAT 1541 1578 HEAT 24.
 REPEAT 1583 1620 HEAT 25.
 REPEAT 1623 1660 HEAT 26.
 REPEAT 1751 1788 HEAT 27.
 REPEAT 1826 1863 HEAT 28.
 MOD_RES 1213 1213 Phosphoserine.
 MOD_RES 1683 1683 Phosphoserine.
 MOD_RES 1691 1691 Phosphothreonine.
 MOD_RES 1692 1692 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Proteasome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1890 AA 
Protein Sequence
METGPNAEIE LLERVLLRLG NADSDEKLEA AVGKFLTPVI LKMNSPHNVV RTKVVEVLTH 60
IKRRLSSRGH VQIPVEALLD QYAAQDSSTF LKNFAIIFIT MGFPRLALEQ QTALASKVVG 120
CEDKLESYQD KLFALLLPVL SDMKIPDDPT QRSKLLDLQD KPAICANFLA LLQDVLLLPY 180
GITQEQDVPP GLSPYSFTRI IAYNWRAEEL EKVKKGIVRF LCASVFSDLQ IFVPLVVASA 240
DTRFSVATPA ITELSKLCTM LDFSNPAVTA PLYTLFAGNQ SKITDRQTRP CCARVRQKLL 300
QYLIKCRGKS INVTKGLQVT FDGFFGTNTN QKCKVLALQF MELLLRDGPR ELVSKVSKVI 360
LTGITKIIGR DSNEPNDVQN AAYSALAQHA RSFPQDVSQD LKLVLGYFNN LASCAPELHS 420
SIREALVSMA PAFAWKTKEK SDAMEVDKNV DSSSVKLDGQ QHLLLAMLLD NAESKVQIVQ 480
NVTSVFLTSC YPEYYAPARY LLLLIAGERN SLRENVTTYL YGTSKKDHIN YSMLSSIDHS 540
KNRISSESIS DFNHLSLEQR RVMLPSFQVM MSHVHEMAEK RLKKNTACVV VGRTKLPYSL 600
EVYEELLDYL RLCLWYSAGV VAAPGDEKYT HELREYITLH YEDTEDNALH QYAQFVQRSV 660
EAKRSESNLI CLYDLLNAAP ELFAAKQLHL LEPLGNTLKD VSETMRINVA QVYGILWAFG 720
LSDEKFDEEV GECLNSLTQK TLEHKHGWLL VVGHTFNRKI AMLKQENKTK DFAAWPQFVN 780
AVKIISKCLC ESQWLLVSAA VKCISMIGKA VEIPNVPVEI QVPSKDGDDD DEEMTEYTSI 840
DSSTKLVIFG VVFQLLRSSS ARQKIREDSA RCLGYLAIGD GEHFTKRNLD KFLTLTKIQK 900
DAALNIAISE AIVNTLCGYD VNKGQPDEKF VNKHCNDDDF DQFLNSLIRL VTDPNPHSRQ 960
AISVWLLAVV KHCSQRPAVL AKKELLQFAF TELLSDDSEF VQDVASRGLG LVYSISDSGS 1020
QSDLANSLLD QLIGGKRKVN QVTADTELFA EGMLGKTPTG GNITTYKELC SLASDLNQPD 1080
MIYQFMQLAN HNATWTSKLG AAFGLKTLSA ESRQKMEPYL GKIIPRLYRY KYDPTPKIQN 1140
SMISIWDTIV TDSKEVTERY YWEILRELLD NLTCKEWRVR IACCLAVRDL LNRPNGLKLR 1200
SEEPVRRALP DNSMEVDEVP EPELKELWFQ LFRVMDDIHE GTRVAAHGTA SFLGKLCVIA 1260
SSSDHGKSGT AVASSILPFL LETGVGHKVP EIRRVSIKTI SDMIDSSGSL IAPHLATLIP 1320
CLLRATGELE NTKLSYVSTR LGADNEAQEA VDTLRAEAAK SLHTMETIGK CVRYIDYSVL 1380
EKMTPEVLEL MKGSVNLGTK IGCAHFVCLI SIRLGKEMTP LVGKYIRACF VGIKNRNATV 1440
RKYNASAIGH LLGLAKEQSI KSLFTKLEEL YAEQPGNRSI ALTIQSINKR HHELLKDYMD 1500
SMLPLIFFAM HEEPNEETKA NVELWKDLWH DVSPGDAGIR LNLNVIIPKL ESSLTDASWS 1560
RKAQAANAIQ TIATRLSSSL DEPDRLRLIK LLLSGLQGRT FEGKERLLQA LAALTKGLDR 1620
NHQICSSIID AAMREARKRE PVYRTMALAS LGEILDQLEA DRFEEVYNMS WNLLEKKELR 1680
KESDDEDEPN TSQELSADER NKRAQTLNRL KEVVWETLGK SWPRHSIETQ HRYQLFFAEN 1740
CTSILAESTR PVQVSLLAAL TKYIERLHVF DESAQVPDLT QINQEKKIKT EETAPKTREA 1800
IVEKICTDVL AAVALAAGVP HSGLKKEALN IVLMLIKRLS GSGNGNQQPL RLIKQSFESN 1860
LEKFQRDSAP EIRCRIKDIE DKLSKLNPQN 1890 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0000502; C:proteasome complex; ISS:UniProtKB. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR026827; ECM29/GCN1.
 IPR024372; Proteasome_stabil_ECM29. 
Pfam
 PF13001; Ecm29 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS